以双下肢无力为首发表现的系统性红斑狼疮伴多系统受累1例  

A Case of Systemic Lupus Erythematosus with Multi-system Involvement Presenting with Bilateral Lower Limb Weakness as the First Manifestation

作　　者：李保林 陈丹丹[1] 李宗锋[1] 袁宝军[2] LI Baolin;CHEN Dandan;LI Zongfeng;YUAN Baojun(Department of Laboratory,First Hospital of Qinhuangdao,Qinghuangdao 066000,China;Department of Laboratory,Kailuan General Hospital,Tangshan 063000,China)

机构地区：[1]秦皇岛市第一医院检验科,河北秦皇岛066000 [2]开滦总医院检验科,河北唐山063000

出　　处：《标记免疫分析与临床》2024年第5期978-980,共3页Labeled Immunoassays and Clinical Medicine

摘　　要：系统性红斑狼疮(SLE)是一种多系统受累、临床表现多样的自身免疫性疾病。多以器官受累后的症状为首发表现就诊。目前,以双下肢无力为首发表现的SLE伴多系统受累的案例较少。本文报道1例20岁女性以双下肢无力为首发表现的SLE患者,伴肌肉受损、血液系统受累、抗磷脂综合征(APS)和肝脏受累。以便为这类疾病的临床诊断提供参考。Systemic lupus erythematosus(SLE)is an autoimmune disease with multi-system involvement and diverse clinical manifestations.Most of SLE patients present to the hospital with symptoms of organ-or system-based involvements.Currently,there are few cases of SLE with multi-system involvements in which bilateral lower extremity weakness is identified as the first clinical manifestation.In this paper,we report a case of 20 years old of SLE with bilateral lower extremity weakness as the first manifestation,accompanied by muscle damage,hematologic involvement,antiphospholipid syndrome(APS),and hepatic involvement.Our results can provide a useful reference for the clinical diagnosis of SLE.

关 键 词：系统性红斑狼疮 双下肢无力 多系统受累 首发表现 抗磷脂综合征 

分 类 号：R593.241[医药卫生—内科学]