宫安康及雌孕激素联合应用预防宫腔粘连术后再粘连的临床效果  

Clinical effect of combined use of Gongankang and estrogen and progesterone in preventing re-adhesion after surgery for intrauterine adhesion

作　　者：翟焕玲 ZHAI Huan-ling(Jinxiang County People's Hospital,Jining 272200,China)

机构地区：[1]金乡县人民医院,272200

出　　处：《中国现代药物应用》2024年第12期25-28,共4页Chinese Journal of Modern Drug Application

摘　　要：目的分析宫腔用交联透明质酸钠凝胶(商品名:宫安康)及雌孕激素联合应用预防宫腔粘连术后再粘连的临床效果。方法选取宫腔粘连手术患者50例,随机分成对照组和观察组,每组25例。对照组宫腔放置球囊及雌孕激素预防术后再粘连,观察组采用宫安康及雌孕激素预防术后再粘连。对比两组治疗效果、宫腔粘连评分及子宫内膜厚度、月经恢复情况、再粘连发生情况。结果在治疗效果方面,观察组的总有效率96.00%高于对照组的68.00%(P<0.05)。治疗前,两组宫腔粘连评分及子宫内膜厚度相比无显著差异(P>0.05);治疗后,观察组宫腔粘连评分(2.85±0.31)分低于对照组的(4.89±0.65)分,子宫内膜厚度(8.28±1.28)mm高于对照组的(6.41±1.01)mm(P<0.05)。观察组月经量(45.36±7.47)ml、经期时间(5.54±1.23)d均多于对照组的(38.12±4.11)ml、(4.03±0.87)d,月经复潮时间(29.65±2.47)d、阴道出血时间(4.21±0.92)d均短于对照组的(34.59±2.73)、(8.40±1.87)d(P<0.05)。在再粘连发生情况方面,观察组的总发生率8.00%低于对照组的40.00%(P<0.05)。结论在宫腔粘连手术后,采用宫安康及雌孕激素联合预防术后再粘连,能使治疗总有效率显著提升,可有效缓解宫腔粘连,改善子宫内膜情况,促进月经恢复,并且可以有效降低再粘连的发生率,临床效果十分理想。Objective To analyze the clinical effect of combined use of intrauterine cross-linked hyaluronate gel(trade name:Gongankang)and estrogen and progesterone in preventing re-adhesion after surgery for intrauterine adhesion.Methods 50 patients with intrauterine adhesions were randomly divided into a control group and an observation group,with 25 cases in each group.The control group received intrauterine balloon placement and treatment with estrogen and progesterone,while the observation group received treatment with Gongankang and estrogen and progesterone.The treatment effects,intrauterine adhesion score and endometrial thickness,menstrual recovery,and the occurrence of adhesions were compared between the two groups.Results In terms of treatment effect,the observation group had higher total effective rate of 96.00%than the control group's 68.00%(P<0.05).Before treatment,there were no significant differences in uterine adhesion score and endometrial thickness between the two groups(P>0.05).After treatment,the observation group had lower uterine adhesion score of(2.85±0.31)points than(4.89±0.65)points in the control group,and higher endometrial thickness of(8.28±1.28)mm than(6.41±1.01)mm in the control group(P<0.05).The observation group had menstrual volume of(45.36±7.47)ml and menstrual duration of(5.54±1.23)d,which were more than(38.12±4.11)ml and(4.03±0.87)d in the control group;the observation group had menstrual recovery time of(29.65±2.47)d and vaginal bleeding time of(4.21±0.92)d,which were shorter than(34.59±2.73)and(8.40±1.87)d in the control group(P<0.05).In terms of the occurrence of re-adhesion,the observation group had lower total incidence of 8.00%than 40.00%in the control group(P<0.05).Conclusion After the surgery for intrauterine adhesions,the combination of Gongankang and estrogen and progesterone can significantly improve the total effective rate of treatment,effectively alleviate intrauterine adhesions,improve endometrial conditions,promote menstrual recovery,and effectively reduce the

关 键 词：宫腔用交联透明质酸钠凝胶 雌孕激素 宫腔粘连 术后再粘连 临床效果 

分 类 号：R713.4[医药卫生—妇产科学]