免疫细胞功能状态量化检测评估与临床应用专家共识  

Expert Consensus on quantify monitoring and assessment of immune cell function status and clinical application

作　　者：中国医疗保健国际交流促进会肝脏移植学分会 中国医疗保健国际交流促进会肾脏移植学分会 中国医药生物技术协会生物诊断技术分会 贺强[2] 李先亮[2] 朱继巧[2] 许文犁 吕少诚[2] 周林 刘喆 王剑锋[2] China International Exchange and Promotive Association for Medical and Health Care(CPAM),Society of Liver Transplantation;China International Exchange and Promotive Association for Medical and Health Care(CPAM),Society of Kidney Transplantation;China Medicinal Biotech Association(CMBA),Society of Biological Diagnostics;He Qiang;Li Xianliang(不详;Beijing Chaoyang Hospital of Capital Medical University,Beijing 100020,China)

机构地区：[1]不详 [2]首都医科大学附属北京朝阳医院,北京100020

出　　处：《器官移植》2024年第4期548-557,共10页Organ Transplantation

基　　金：国家自然科学基金(82370665);北京市自然科学基金(7232068、7232065)。

摘　　要：免疫系统是维持机体器官功能健康和预防疾病的重要保障,免疫健康管理和疾病免疫治疗目标是恢复免疫系统的正常功能状态。免疫学领域研究解决了如何抑制或提高免疫状态的技术性难题,随之带来亟需回答的问题是如何全面地检测和量化评估免疫状态,这是下一个挑战,目前国际上尚无成熟解决方案。免疫状态量化检测与可视化评估对疾病防控、亚健康状态管理和疾病免疫治疗均具有重要意义。本专家共识针对正常免疫状态定义和免疫细胞功能状态(免疫力)全面量化评估及可视化评分技术手段等问题进行了初步讨论,提出了正常免疫状态相关的基础概念和思考,探讨免疫细胞功能状态量化检测评估方向和原则,并以此为契机,推动免疫力解码以及免疫健康领域基础课题和临床试验的深入研究。The immune system is the important guarantee for maintaining the health of organ function and preventing diseases.The goal of immune health management and immune treatment is to restore the normal function of the immune system.The technical problems of how to inhibit or enhance the immune status has been solved in the field of immunology,but how to comprehensively detect and quantitatively evaluate the immune status is still a challenge.There is no mature solution at present.The quantification detection and visualization evaluation of immune status are of great significance for disease prevention and control,sub-health status management,and immune treatment.This expert consensus has carried out preliminary discussions on the definition of normal immune status and the comprehensive quantitative evaluation and visual scoring techniques of immune cell function status(immune function),put forward the basic concepts and thinking related to normal immune status,discussed the direction and principles of quantitative detection and evaluation of immune cell function status,and taken this as an opportunity to promote the decoding of immunity and the study of basic and clinical trials in the field of immune health.

关 键 词：免疫力 免疫细胞 免疫评估 免疫治疗 健康管理 

分 类 号：R617[医药卫生—外科学] R392.4[医药卫生—临床医学]