Ⅰ类切口围术期抗菌药物预防使用合理性分析  

Analysis on the Rationality of Prophylactic Use of Antibiotics during the Perioperative Period of Class Ⅰ Incisions

作　　者：崔晓飞 CUI Xiaofei(Department of Pharmacy,Puyang Oilfield General Hospital,Puyang Henan 457001,China)

机构地区：[1]濮阳油田总医院药学部,河南濮阳457001

出　　处：《临床研究》2024年第7期48-51,共4页Clinical Research

摘　　要：目的分析濮阳油田总医院Ⅰ类切口围术期抗菌药物预防使用合理性情况,为后续临床抗菌药物的管理提供参考性依据。方法将濮阳油田总医院2023年1月至2023年6月开展的635例行Ⅰ类切口手术患者作为本次研究对象,回顾性分析接受Ⅰ类切口手术患者在围术期接受抗菌药物的治疗效果。结果本次研究中收入的635例Ⅰ类切口手术患者中,共有214例患者使用抗菌药物,针对每个科室Ⅰ类切口患者围术期抗菌药物预防性使用情况进行分析,脊柱外科患者使用抗菌药物占66.04%,神经外科占64.00%,手足与创伤骨科占50.90%;甲状腺血管外科、乳腺外科、疝与腹壁外科与泌尿外科中未使用任何抗菌药物,差异有统计学意义(P<0.05)。Ⅰ类切口围术期使用抗菌药物的种类主要为第一、二代头孢菌素类,以静脉给药为主。共使用抗菌药物7种,其中头孢唑林占59.35%,头孢呋辛占26.17%,差异有统计学意义(P<0.05);抗菌药物合理使用率为86.45%,不合理使用率为13.55%,主要以无指征预防用药、超疗程用药为主,差异有统计学意义(P<0.05)。结论本院接受Ⅰ类切口手术的患者中在围术期采取预防使用抗菌药物情况大部分合理,但仍存在少部分不合理情况,故应加强干预,保证抗菌药物的合理使用,提高抗菌药物合理率,保证患者用药安全。Objective To analyze the rationality of prophylactic use of antibiotics during the perioperative period of Class Ⅰ incisions in Puyang Oilfield General Hospital,and to provide a reference for subsequent clinical management of antibiotics.Methods A total of 635 patients who underwent Class Ⅰ incision surgery in Puyang Oilfield General Hospital from January 2023 to June 2023 were selected as the subjects of this study.The therapeutic effect of antibiotics received by patients undergoing Class I incision surgery during the perioperative period was retrospectively analyzed.Results Among the 635 patients with Class Ⅰ incision surgery included in this study,214 patients used antibiotics.The prophylactic use of antibiotics during the perioperative period of Class I incision patients in each department was analyzed.The use of antibiotics in patients in the spine surgery department accounted for 66.04%,neurosurgery accounted for 64.00%,and hand,foot and trauma orthopedics accounted for 50.90%;no antibiotics were used in thyroid vascular surgery,breast surgery,hernia and abdominal wall surgery,and urology,the difference was statistically significant(P<0.05).The types of antibiotics used during the perioperative period of Class Ⅰ incisions were mainly first and second generation cephalosporins,mainly administered intravenously.A total of 7 kinds of antibiotics were used,among which cefazolin accounted for 59.35%,cefuroxime accounted for 26.17%,the difference was statistically significant(P<0.05);the rational use rate of antibiotics was 86.45%,the irrational use rate was 13.55%,mainly due to prophylactic medication without indications and over-course medication,the difference was statistically significant(P<0.05).Conclusion The prophylactic use of antibiotics during the perioperative period in patients undergoing Class Ⅰ incision surgery in our hospital is mostly rational,but there are still a small part of irrational situations,so intervention should be strengthened to ensure the rational use of antibiotics,improv

关 键 词：Ⅰ类切口 围术期 抗菌药物 合理性 

分 类 号：R978.24[医药卫生—药品]