七氟醚复合艾司氯胺酮在腔镜下患儿腹股沟斜疝疝囊高位结扎术的应用效果  

Efficacy of Sevoflurane plus Esketamine in laparoscopic high ligation of inguinal hernia hernia sac in children

作　　者：王萍 王文 程乐 李云 章征兵[1] WANG Ping;WANG Wen;CHENG Le;LI Yun;ZHANG Zhengbing(Department of Anaesthesia,Jiangxi Children's Hospital,Jiangxi Province,Nanchang,330006,China;Department of Orthopaedics,Jiangxi Children's Hospital,Jiangxi Province,Nanchang330006,China)

机构地区：[1]江西省儿童医院麻醉科,江西南昌330006 [2]江西省儿童医院骨科,江西南昌330006

出　　处：《中国当代医药》2024年第18期86-89,共4页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(202110103)。

摘　　要：目的分析七氟醚复合艾司氯胺酮在腔镜下患儿腹股沟斜疝疝囊高位结扎术中的应用效果。方法选取2021年3月至2022年7月江西省儿童医院收治的82例腹股沟斜疝疝囊高位结扎术的患儿为研究对象,按照随机数字表法分为对照组(41例)与观察组(41例)。对照组采用丙泊酚复合艾司氯胺酮麻醉,观察组采用七氟醚复合艾司氯胺酮麻醉。比较两组各时间点血流动力学变化、术后恢复情况、术后躁动、恶心等发生情况。结果麻醉后5 min(T_(1))、手术5 min(T_(2))、术毕(T_(3))时刻观察组平均动脉压、心率均低于对照组,差异有统计学意义(P<0.05)。观察组艾司氯胺酮用量、麻醉时间及苏醒时间均低于对照组,差异有统计学意义(P<0.05)。观察组不良反应总发生率低于对照组,差异有统计学意义(P<0.05)。结论行腔镜下腹股沟斜疝疝囊高位结扎术患儿应用七氟醚复合艾司氯胺酮麻醉处理效果更佳,对患儿的血压、心率等影响较小,有利于血流动力学的稳定,缩短苏醒时间,并降低苏醒期躁动发生率,有较高应用价值。Objective To analyze the effect of Sevoflurane combined with Esketamine in the high ligation of the hernia sac in children with oblique inguinal hernia under endoscopy.Methods Eighty-two children with 2021 hernia inguinal hernia underwent high ligation from March to July 2022 in Jiangxi Children's Hospital,they were divided into control group(n=41)and observation group(n=41)according to random number table method.The control group was anesthetized with Propofol combined with Esketamine,and the observation group was anesthetized with Sevoflurane combined with Esketamine.The hemodynamic changes,postoperative recovery,postoperative agitation and nausea were compared between the two groups at each time point.Results The mean arterial pressure and heart rate in the observation group were lower than those in the control group 5 min after anesthesia(T_(1)),5 min after surgery(T_(2)),and after surgery(T_(3))(P<0.05).The dosage of Esketamine,anesthesia time and recovery time in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group(24.39%),and the difference was statistically significant(P<0.05).Conclusion Sevoflurane combined with Esketamine is more effective in the management of inguinal hernia hernia sac in children undergoing laparoscopic high ligation.It has less effect on blood pressure and heart rate,and is beneficial to the stability of Hemodynamics,it has high application value to shorten the time of waking up and reduce the incidence of restlessness in waking period.

关 键 词：腔镜下腹股沟斜疝疝囊高位结扎术 七氟醚 艾司氯胺酮 血流动力学 

分 类 号：R614[医药卫生—麻醉学]