元胡止痛滴丸超前镇痛在膝关节镜探查手术中的临床应用观察  

Clinical observation on the preemptive analgesia of Yuanhu Zhitong Dropping Pills in knee arthroscopic exploration surgery

作　　者：吕艳敏 柴世权 缪倩 LYU Yanmin;CHAI Shiquan;MIAO Qian(Department of Anesthesiology,Shangrao People's Hospital,Jiangxi Province,Shangrao334000,China)

机构地区：[1]江西省上饶市人民医院麻醉科,江西上饶334000

出　　处：《中国当代医药》2024年第18期90-93,97,共5页China Modern Medicine

基　　金：江西省中医药管理局科技计划项目(2023A0050)。

摘　　要：目的探讨元胡止痛滴丸超前镇痛在膝关节镜探查手术中的临床应用效果。方法选取2020年1月至2022年12月在上饶市人民医院行择期膝关节镜探查手术的70例患者作为研究对象,按照随机数字表法分为对照组(35例)与观察组(35例),对照组围手术期给予常规方法镇痛,观察组在对照组基础上增加元胡止痛滴丸超前镇痛。比较两组不同时间点生命体征、术后疼痛情况、术后48 h内补救镇痛次数、膝关节活动度及不良反应发生情况。结果两组入室时、麻醉10 min、麻醉30 min、术毕时平均动脉压(MAP)、心率(HR)水平比较,差异有统计学意义(P<0.05);两组中各时间点血氧饱和度(SpO_(2))水平比较,差异无统计学意义(P>0.05)。观察组术后2、6、12、24 h时静息及活动时视觉模拟评分法(VAS)分值均低于对照组,观察组术后48 h内补救镇痛人数少于对照组,差异有统计学意义(P<0.05);观察组术前2 h、入室时、术后2、24、48 h膝关节活动度与对照组比较,差异均无统计学意义(P>0.05)。两组的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论元胡止痛滴丸超前镇痛在膝关节镜探查手术中能稳定患者生命体征,降低术后疼痛,未见其他严重不良反应。Objective To investigate the clinical effect of preemptive analgesia with Yuanhu Zhitong Dropping Pills in knee arthroscopic exploration surgery.Methods Seventy patients who underwent elective knee arthroscopic exploration surgery in Shangrao City People's Hospital from January 2020 to December 2022 were selected as the research objects and divided into a control group(35 cases)and an observation group(35 cases)using random number table method.The control group received routine analgesia during the perioperative period,while the observation group received advanced analgesia with Yuanhu Zhitong Dropping Pills in addition to the control group.The vital signs,postoperative pain,frequency of relief analgesia within 48 hours,knee joint range of motion,and incidence of adverse reactions between two groups at different time points were compared.Results The average arterial pressure(MAP)and heart rate(HR)levels at the time of entry,10 minutes of anesthesia,30 minutes of anesthesia,and completion of surgery were significant between the two groups,with statistically significant differences(P<0.05).There was no statistically significant difference in blood oxygen saturation(SpO_(2))levels at each time point between the two groups(P>0.05).The visual analogue scale(VAS)scores at rest and activity in the observation group were lower than those in the control group at 2,6,12,and 24 hours after surgery,in the comparison of the number of people receiving relief analgesia within 48 hours after surgery between the two groups,the number of people in the observation group was lower than that in the control group,with statistically significant differences(P<0.05).There was no statistically significant difference in knee joint range of motion between the observation group and the control group at 2 hours before surgery,upon entry,2 hours,24 hours,and 48 hours after surgery(P>0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Yuanhu Zhitong Droppi

关 键 词：元胡止痛滴丸 超前镇痛 膝关节镜探查手术 疼痛 

分 类 号：R614[医药卫生—麻醉学]