药学服务干预对于2型糖尿病性肾病患者的应用效果及安全性  

Application effectiveness and safety of pharmaceutical service intervention on type 2 diabetes nephropathy patients

作　　者：李利华 刘华清[1] LI Lihua;LIU Huaqing(Department of Pharmacy,Huizhou Hospital of Traditional Chinese Medicine,Guangdong Province,Huizhou516001,China)

机构地区：[1]广东省惠州市中医医院药学部,广东惠州516001

出　　处：《中国当代医药》2024年第18期94-97,共4页China Modern Medicine

摘　　要：目的探讨药师参与药学服务对2型糖尿病性肾病患者的用药有效性、安全性和经济性影响。方法选取2022年3月至2023年3月惠州市中医医院内分泌科收治的60例2型糖尿病性肾病患者作为研究对象,按照随机数字表法分为对照组(n=30)和干预组(n=30),比较两组患者的空腹血糖、餐后2 h血糖、糖化血红蛋白水平、用药依从性、不良反应发生率及用药费。结果干预组的空腹血糖、餐后2 h血糖、糖化血红蛋白水平均低于对照组,差异有统计学意义(P<0.05)。干预组用药依从性优于对照组,差异有统计学意义(P<0.05)。干预组不良反应总发生率低于对照组,差异有统计学意义(P<0.05)。干预组患者用药费用低于对照组,差异有统计学意义(P<0.05)。结论2型糖尿病性肾病患者在通过药师参与药学服务后,药物疗效提高,药物不良反应或事件发生率下降,患者依从性提高,药物治疗费用减少。Objective To investigate the effects of pharmaceutical service intervention on the effectiveness,safety,and economy of medication administration in patients with type 2 diabetes nephropathy.Methods A total of 60 patients with type 2 diabetic nephropathy admitted to Department of Pharmacy of Huizhou Hospital of Traditional Chinese Medicine from March 2022 to March 2023 were selected as research objects.They were divided into control group(n=30)and intervention group(n=30)according to random number table method.Fasting blood glucose,2 h postprandial blood glucose,glycated hemoglobin level,medication compliance,incidence of adverse reactions and drug cost were compared between the two groups.Results The levels of fasting blood glucose,2 h postprandial blood glucose and glycated hemoglobin in the intervention group were lower than those in the control group,and the differences were statistically significant(P<0.05).Medication compliance in the intervention group was better than that in the control group,and the difference was statistically significant(P<0.05).The total incidence of adverse reactions in the intervention group was lower than that in the control group,the difference was statistically significant(P<0.05).The medication cost in the intervention group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion After patients with type 2 diabetic nephropathy participate in pharmaceutical service intervention through pharmacists,drug efficacy is improved,the incidence of adverse drug reactions or events is decreased,patients'compliance is improved,and drug treatment costs are reduced.

关 键 词：药学服务干预 2型糖尿病性肾病 应用效果 安全性 

分 类 号：R95[医药卫生—药学]