复方嗜酸乳杆菌联合补锌治疗应用于小儿腹泻的价值研讨  

Study on the Value of Compound Lactobacillus Acidophilus Combined with Zinc Supplementation Therapy in the Application of Pediatric Diarrhea

作　　者：付红霞 齐文举 晋红蕾 FU Hongxia;QI Wenju;JIN Honglei(Department of Pediatrics,Shanghe County Hospital of Traditional Chinese Medicine,Jinan,Shandong Province,251600 China)

机构地区：[1]商河县中医医院儿科,山东济南251600

出　　处：《系统医学》2024年第10期142-144,149,共4页Systems Medicine

摘　　要：目的分析复方嗜酸乳杆菌联合补锌治疗应用于小儿腹泻的价值。方法选取2020年3月—2022年11月商河县中医医院收治的80例小儿腹泻患儿为研究对象。以抽签法分为两组,各40例。对照组给予复方嗜酸乳杆菌治疗,观察组在对照组基础联合葡萄糖酸锌治疗。比较两组临床疗效、免疫功能、血锌、症状改善时间及血清营养指标。结果观察组临床总有效率为97.50%,高于对照组80.00%,差异有统计学意义(χ^(2)=4.507,P=0.034)。治疗后,观察组免疫球蛋白A、免疫球蛋白G、免疫球蛋白M、血锌水平高于对照组,差异有统计学意义(P均<0.05)。观察组症状缓解时间及住院时间短于对照组,差异有统计学意义(P均<0.05)。观察组清蛋白、血红蛋白水平高于对照组,差异有统计学意义(P均<0.05)。结论小儿腹泻应用复方嗜酸乳杆菌联合补锌治疗能有效提高患儿治疗效果,并有助于症状早期改善,且提高免疫功能,纠正营养不良。Objective To analyze the value of compound Lactobacillus acidophilus combined with zinc supplementa⁃tion therapy applied to pediatric diarrhea.Methods 80 children with diarrhea treated in Shanghe County Hospital of Traditional Chinese Medicine from March 2020 to November 2022 were selected as the study objects.They were di⁃vided into two groups with 40 cases each.The control group was treated with compound Lactobacillus acidophilus,and the observation group was treated with zinc gluconate.The clinical efficacy,immune function,blood zinc,symptom im⁃provement time and serum nutrition indexes were compared between the two groups.Results The clinical total effec⁃tive rate of the observation group was 97.50%,higher than that of the control group 80.00%,and the difference was statistically significant(χ^(2)=4.507,P=0.034).After treatment,the levels of immunoglobulin A,immunoglobulin G,im⁃munoglobulin M and blood zinc in the observation group were higher than those in the control group,and the differ⁃ences were statistically significant(all P<0.05).The duration of symptom remission and hospitalization in the observa⁃tion group were shorter than that in the control group,and the differences were statistically significant(both P<0.05).The levels of albumin and hemoglobin in observation group were higher than those in control group,and the differ⁃ences were statistically significant(both P<0.05).Conclusion The application of compound Lactobacillus acidophilus combined with zinc supplementation for pediatric diarrhea can effectively improve the therapeutic effect of the chil⁃dren and help the early improvement of the symptoms,as well as enhance the immune function and correct malnutri⁃tion.

关 键 词：复方嗜酸乳杆菌 补锌 小儿腹泻 

分 类 号：R725.7[医药卫生—儿科]