2364例泌尿生殖道感染者支原体感染情况及耐药性分析  

Analysis of Mycoplasma infection and drug resistance in 2364 cases of urinary and reproductive tract infections

作　　者：刘艳丽[1] 李冰[1] 张绍佳 LIU Yanli;LI Bing;ZHANG Shaojia(Xinxiang Central Hospital,Xinxiang453000,Henan,China)

机构地区：[1]新乡市中心医院,河南新乡453000

出　　处：《中国病原生物学杂志》2024年第7期828-832,共5页Journal of Pathogen Biology

摘　　要：目的 探析新乡地区2 364例泌尿生殖道感染者支原体感染情况及耐药性。方法 选取2022-2023年,本院皮肤病科、妇产科、泌尿外科等门诊疑似泌尿生殖道感染患者送检的泌尿生殖道标本共2 364例。采集患者标本后,采用试剂盒进行支原体培养及药敏试验。结果 2 364例送检标本中,支原体总阳性率32.99%(780/2364),单纯性Uu阳性率26.35%(623/2 364),单纯性Mh阳性率4.02%(95/2364),Uu+Mh混合阳性率2.62%(62/2364)。2022年支原体总阳性率、单纯性Uu阳性率、单纯性Mh阳性率、Uu+Mh混合阳性率分别为30.91%(327/1058)、24.86%(263/1058)、3.59%(38/1058)、2.46%(26/1058);2023年分别为34.69%(453/1306)、27.57%(360/1306)、4.36%(57/1306)、2.76%(36/1306);不同年份支原体阳性率差异无统计学意义(均P>0.05)。男性支原体总阳性率、单纯性Uu阳性率、单纯性Mh阳性率、Uu+Mh混合阳性率分别为20.20%(40/198)、17.17%(34/198)、1.01%(2/198)、2.02%(4/198);女性分别为34.16%(740/2166)、26.27%(569/2166)、4.29%(93/2166)、2.68%(58/2166)。不同性别支原体的总阳性率、单纯性Uu阳性率、单纯性Mh阳性率差异有统计学意义(均P<0.05),Uu+Mh混合感染阳性率差异无统计学意义(P>0.05)。<20岁支原体总阳性率为29.45%(48/163),单纯性Uu阳性率29.45%(48/163),未检出单纯Mh阳性及Uu+Mh混合阳性;20~30岁支原体总阳性率、单纯性Uu阳性率、单纯性Mh阳性率、Uu+Mh混合阳性率分别为38.03%(440/1157)、29.99%(347/1157)、5.01%(58/1157)、3.03%(35/1157);31~40岁分别为35.95%(252/701)、28.96%(203/701)、3.85%(27/701)、3.14%(22/701);41~50岁分别为11.22%(34/303)、6.93%(21/303)、2.97%(9/303)、1.32%(4/303);>50岁分别为15.00%(6/40)、10.00%(4/40)、2.50%(1/40)、2.50%(1/40)。不同年龄段支原体的总阳性率、单纯性Uu阳性率、单纯性Mh阳性率差异有统计学意义(均P<0.05),Uu+Mh混合感染阳性率差异无统计学意义(P>0.05)。单纯Uu阳性标本对左氧氟沙星、环丙沙星的耐药�Objective To explore the situation and drug resistance of Mycoplasma infection in 2364 cases ofthe urinary and reproductive tract in Xinxiang area.Methods A total of 2364 urogenital tract specimens were selected from suspected urogenital infection patients in outpatient departments such as dermatology,obstetrics and gynecology,and urology of our hospital from 2022 to 2023.After collecting patient specimens,Mycoplasma culture and drug sensitivity tests were conducted by a reagent kit.Results Among the 2364 samples submitted for testing,the total positive rate of Mycoplasma was 32.99%(780/2364),the pure Uu positive rate was 26.35%(623/2364),the pure Mh positive rate was 4.02%(95/2364),and the mixed Uu+Mh positive rate was 2.62%(62/2364).In 2022,the total positive rate of Mycoplasma,pure Uu positive rate,pure Mh positive rate,and Uu+Mh mixed positive rate were 30.91%(327/1058),24.86%(263/1058),3.59%(38/1058),and 2.46%(26/1058),respectively;In 2023,they were 34.69%(453/1306),27.57%(360/1306),4.36%(57/1306),and 2.76%(36/1306),respectively;There was no statistically significant difference in the positive rate of Mycoplasma among different years(all P>0.05).The total positive rate,simple Uu positive rate,simple Mh positive rate,and Uu+Mh mixed positive rate of male mycoplasma were 20.20%(40/198),17.17%(34/198),1.01%(2/198),and 2.02%(4/198),respectively;Women were 34.16%(740/2166),26.27%(569/2166),4.29%(93/2166),and 2.68%(58/2166),respectively.The total positive rateof Mycoplasma,pure Uu positive rate,and pure Mh positive rate from different genders showed statistically significant differences(all P<0.05),while the positive rate of mixed Uu+Mh infection did not show statistically significant differences(P>0.05).The total positive rate of Mycoplasma under 20 years old was 29.45%(48/163),and the pure Uu positive rate was 29.45%(48/163).No pure Mh positive or mixed Uu+Mh positive cases were detected;The total positive rate of Mycoplasma,pure Uu positive rate,pure Mh positive rate,and Uu+Mh mixed positive rate from 20 to 30

关 键 词：泌尿生殖道 解脲脲原体 人型支原体 耐药性 

分 类 号：R691.3[医药卫生—泌尿科学]