运中汤治疗危重症患者脾虚浊毒型急性胃肠功能障碍临床研究  

Yunzhong Decoction in the Treatment of Acute Gastrointestinal Dysfunction of Spleen Dampness Turbid Toxicity in Critically Ill Patients

作　　者：郭宇菁 张洁 王素娟 GUO Yujing;ZHANG Jie;WANG Sujuan(Department of Intensive Care Medicine,Shanxi Hospital of Integrated Traditional Chinese and Western Medicine,Shanxi Province,Taiyuan 030001,China;Department of Internal Medicine,Shanxi Hospital of Integrated Traditional Chinese and Western Medicine,Shanxi Province,Taiyuan 030001,China)

机构地区：[1]山西省中西医结合医院重症医学科,山西太原030001 [2]山西省中西医结合医院普通内科,山西太原030001

出　　处：《光明中医》2024年第12期2386-2389,共4页GUANGMING JOURNAL OF CHINESE MEDICINE

基　　金：山西省卫生健康科研课题(No.2022104)。

摘　　要：目的 探讨运中汤治疗危重症患者胃肠功能障碍(脾虚浊毒型)的临床疗效。方法 选取危重症合并胃肠功能障碍(脾虚浊毒型)患者80例,按照随机数字表法分为2组。对照组(40例)予西医基础治疗,观察组(40例)在对照组治疗基础上加用运中汤加减治疗。比较2组患者疾病治疗效果及胃肠功能恢复情况,评价其临床疗效。结果 观察组治疗后的临床疗效较对照组明显提高;腹内压、ICU治疗时间、APACHE-II评分、机械通气时间、血乳酸、胃泌素较对照组明显下降,胃蛋白酶较对照组升高,差异有统计学意义(P<0.05)。结论 运用运中汤可改善危重症合并胃肠功能障碍患者的胃肠功能,改善患者预后,为危重症患者胃肠功能障碍的治疗提供了新的思路及可行性。Objective To investigate the clinical efficacy of Yunzhong decoction in the treatment of gastrointestinal dysfunction(spleen dampness turbid toxicity type)in critically ill patients.Methods The critically ill patients with gastrointestinal dysfunction(spleen dampness turbid toxicity type)80 cases were selected,and randomly divided into 2 groups.The control group(n=40)was treated with Western medicine,and the observation group(n=40)was treated with Yunzhong decoction on the basis of control group.The therapeutic effect and gastrointestinal function recovery of the two groups were compared,and the clinical effect was evaluated.Results The clinical efficacy,internal abdominal pressure,ICU treatment time,APACHE-II score,mechanical ventilation time and intestinal mucosal barrier function in the observation group were significantly decreased compared with the control group,and the difference was statistical significance(P<0.05).Conclusion The application of Yunzhong decoction can improve the gastrointestinal function and prognosis of critically ill patients with gastrointestinal dysfunction,and provide a new idea and feasibility for the treatment of gastrointestinal dysfunction in critically ill patients.

关 键 词：急性胃肠功能障碍 脾虚浊毒证 运中汤 危重症患者 

分 类 号：R278[医药卫生—中医学]