有机化学中的成环反应及其逆合成分析  

Analysis of Cycling Reactions and Reverse Synthesis in Organic Chemistry

作　　者：王清花 Wang Qinghua(Shanxi University of Electronic Science and Technology,Linfen Shanxi 041000,China)

机构地区：[1]山西电子科技学院,山西临汾041000

出　　处：《山西化工》2024年第6期13-14,31,共3页Shanxi Chemical Industry

基　　金：山西省高等学校教学改革创新项目(J20221542)。

摘　　要：为了深入理解有机化学中关键成环反应机制、优化反应条件及逆合成分析在合成路径设计中的应用,本研究采用了实验和理论相结合方法。以Diels-Alder反应、Mizoroki-Heck反应、环加成反应为例,分析了成环反应的实施步骤、产物的分离与纯化技术及产物结构鉴定技术。结果表明,精确控制实验条件可提高成环反应的产率,逆合成分析应用为合成路径优化提供了实践指导,研究发现为有机化学领域提供了新视角。In order to gain a deeper understanding of the key cyclization reaction mechanisms in organic chemistry,optimize reaction conditions,and apply reverse synthesis analysis in synthesis pathway design,this study adopted a combination of experimental and theoretical methods.Taking Diels Alder reaction,Mizoroki Heck reaction,and cycloaddition reaction as examples,the implementation steps of cyclization reaction,product separation and purification technology,and product structure identification technology were analyzed.The results indicate that precise control of experimental conditions can improve the yield of cyclization reactions,and the application of reverse synthesis analysis provides practical guidance for optimizing synthesis paths.Research findings can provide a new perspective for the field of organic chemistry.

关 键 词：成环反应 反应机理 分离 

分 类 号：O626[理学—有机化学]