新型冠状病毒无症状感染患者心脏瓣膜手术围手术期结果分析  

Perioperative results of cardiac valve surgery in patients with asymptomatic SARS-CoV-2 infection

作　　者：王笑晨 孙海磊 张超宇 周正春 魏宇 宣海洋 程光存 葛建军 WANG Xiaochen;SUN Hailei;ZHANG Chaoyu;ZHOU Zhengchun;WEI Yu;XUAN Haiyang;CHENG Guangcun;GE Jianjun(Department of Cardiovascular Surgery,The First Affiliated Hospital of University of Science and Technology of China,Hefei,230000,P.R.China;Anhui Medical University,Hefei,230000,P.R.China)

机构地区：[1]中国科学技术大学附属第一医院(安徽省立医院)心脏大血管外科,合肥230000 [2]安徽医科大学,合肥230000

出　　处：《中国胸心血管外科临床杂志》2024年第7期962-966,共5页Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

基　　金：安徽省重点研究与开发计划(202004j07020018)。

摘　　要：目的 分析无症状新型冠状病毒(新冠)感染患者心脏瓣膜手术围手术期治疗结果。方法 回顾性分析2022年11月—2023年2月中国科学技术大学附属第一医院心脏大血管外科接受心脏瓣膜置换患者的围手术期临床资料。根据患者是否感染新冠,将患者分为未感染组和无症状感染组。比较两组患者围手术期相关数据,分析新冠无症状感染对心脏瓣膜置换手术治疗结果的影响。结果 共纳入66例患者,其中男36例、女30例,平均年龄(58.0±11.1)岁。未感染组51例,无症状感染组15例。2例二尖瓣置换、20例主动脉瓣置换、1例双瓣置换、3例主动脉瓣置换加三尖瓣成形、22例二尖瓣置换加三尖瓣成形、18例双瓣置换加三尖瓣成形。无症状感染患者比未感染患者急诊手术比例更高(26.7%vs.0.0%,P<0.01)。无症状感染和未感染患者术中体外循环时间、主动脉阻断时间、呼吸机辅助时间、ICU停留时间、术后引流量以及术后相关并发症差异均无统计学意义(P>0.05)。结论 新冠无症状感染和未感染患者心脏瓣膜手术的围手术期结果基本一致。Objective To analyze the perioperative outcomes of cardiac valve surgery in patients with asymptomatic SARS-CoV-2 infection.Methods The perioperative clinical data of patients receiving heart valve replacement in the Department of Cardiovascular Surgery,the First Affiliated Hospital of University of Science and Technology of China from November 2022 to February 2023 were retrospectively analyzed.According to whether the patients were infected with SARS-CoV-2,they were divided into a non-infected group and an asymptomatic group.The perioperative data of the patients were compared between the two groups,and the effect of asymptomatic infection on the result of heart valve replacement surgery was analyzed.Results A total of 66 patients were enrolled including 36 males and 30 females with a mean age of 58.0±11.1 years.There were 51 patients in the non-infected group and 15 patients in the asymtomatic group.There were 2 patients of mitral valve replacement,20 patients of aortic valve replacement,1 patient of double valve replacement,3 patients of aortic valve replacement with tricuspid valvoplasty,22 patients of mitral valve replacement and tricuspid valvoplasty,18 patients of double valve replacement and tricuspid valvoplasty.Asymptomatic infected patients received more emergency surgery than uninfected patients(26.7% vs.0.0%,P<0.01).There was no statistical difference in the duration of extracorporeal circulation,aortic occlusion,mechanical ventilation time after the surgery,ICU stay,postoperative drainage volume,or postoperative complications between the two groups.Conclusion Peri-operative results of cardiac valve surgery in patients with asymptomatic SARS-CoV-2 infection and non-infection are almost the same.

关 键 词：新型冠状病毒 无症状感染 心脏瓣膜手术 围手术期 

分 类 号：R654.2[医药卫生—外科学] R511[医药卫生—临床医学]