Modular-integrative modeling:a new framework for building brain models that blend biological realism and functional performance  被引量:1

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作  者:Mario Senden Sacha J.van Albada Giovanni Pezzulo Egidio Falotico Ibrahim Hashim Alexander Kroner Anno C.Kurth Pablo Lanillos Vaishnavi Narayanan Cyriel Pennartz Mihai A.Petrovici Lea Steffen Tonio Weidler Rainer Goebel 

机构地区:[1]Department of Cognitive Neuroscience,Maastricht University,The Netherlands [2]Maastricht Brain Imaging Centre,Maastricht University,The Netherlands [3]Institute of Neuroscience and Medicine(INM-6)and Institute for Advanced Simulation(IAS-6)and JARA-Institut Brain Structure-Function Relationships(INM-10),Jülich Research Center,Germany [4]Institute of Zoology,University of Cologne,Germany [5]Institute of Cognitive Sciences and Technologies,National Research Council,Italy [6]The BioRobotics Institute,Scuola Superiore Sant’Anna,Italy [7]RWTH Aachen University,Germany [8]Donders Institute for Brain,Cognition and Behavior,Radboud University,The Netherlands [9]Cognitive and Systems Neuroscience Group,Swammerdam Institute for Life Sciences,University of Amsterdam,The Netherlands [10]Department of Physiology,University of Bern,Switzerland [11]FZI Research Center of Information Technology,Germany

出  处:《National Science Review》2024年第5期6-9,共4页国家科学评论(英文版)

基  金:supported by the European Union’s Horizon 2020 Framework Programme for Research and Innovation(Human Brain Project SGA3,945539).

摘  要:To cope with the immense complexity of the brain,neuroscientific research often focuses on isolated brain structures or circumscribed perceptual,cognitive or motor functions[1].This reductionist approach overlooks the intricate and multifaceted interplay among various structural and functional components.For instance,even simple movements require the coordinated activation of numerous neuronal populations across multiple brain regions[2].Furthermore,and importantly,this approach ignores the complex interactions between the brain,the body and the environment,despite the significant role the latter two play in shaping cognition and perception[3].

关 键 词:FUNCTIONAL latter instance 

分 类 号:TB383.4[一般工业技术—材料科学与工程]

 

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