重新肆虐的百日咳给临床诊治带来新挑战  

The resurgence of pertussis has brought new challenges to clinical diagnosis and treatment

作　　者：武文艳[1] 关育红 刘晶哲 Wu Wenyan;Guan Yuhong;Liu Jingzhe(Department of Pediatrics,Beijing Huaxin Hospital,Beijing 100016,China;National Center for Children's Health,China,Department No.2 of Respiratory Medicine,Beijing Childen's Hospital,Capital Medical University,Beijing 100045,China;Department of Radiology,Beijing Huaxin Hospital,Beijing 100016,China)

机构地区：[1]北京华信医院儿科,北京100061 [2]首都医科大学附属北京儿童医院呼吸二科,国家儿童医学中心,北京100045 [3]北京华信医院放射科,北京100061

出　　处：《新发传染病电子杂志》2024年第3期1-4,共4页Electronic Journal of Emerging Infectious Diseases

摘　　要：百日咳是一种由百日咳鲍特菌感染引起的呼吸道传染性疾病,属于国家法定传染病中的乙类传染病之一。20世纪60-70年代,我国百日咳的发病率达到了10~20/万,给人民的身体健康和生命安全带来了巨大的威胁。自1978年以来我国在全国范围内广泛开展百日咳疫苗接种后,百日咳的发病率和死亡率大幅下降。但据国家疾病预防控制局公布的最新全国法定传染病疫情数据显示,近年来百日咳有卷土重来之势。年长儿童发病率逐年上升,小婴儿感染率也有明显上升趋势,且小婴儿感染症状重,可能发生窒息、心脏停搏等严重并发症甚至死亡,极大地影响了儿童身体健康和生命安全。本述评结合临床病例,就百日咳流行现状、主要临床表现、诊断要点、治疗方案的选择原则和疫苗接种及预防措施等内容进行系统阐述,对临床工作具有指导意义。Pertussis is a respiratory infectious disease caused by Bordetella pertussis infection,which is one of the Class B infectious diseases in the national notifiable infectious diseases.,60-70s of the 20th century,the incidence of whooping cough in China was very high,reaching 10-20/10000,which brought a huge threat to people's health and life safety.Since 1978,when pertussis vaccine was widely administered nationwide,the incidence and mortality of pertussis have dropped significantly.However,according to the latest national epidemic data on notifiable infectious diseases released by the National Bureau of Disease Control and Prevention,whooping cough has made a comeback in recent years.The incidence of older children is increasing year by year,and the infection rate of young infants is also on the rise,and the infection symptoms of young infants are severe,and serious complications such as suffocation and cardiac arrest and even death may occur,which greatly affects the health and life safety of children.Based on clinical cases,this article systematically expounds the current situation of pertussis,the main clinical manifestations,diagnosis,the selection principles of treatment regimens,and vaccination and preventive measures,which has important guiding significance for clinical work.

关 键 词：百日咳 流行病学 诊治 预防 

分 类 号：R516.6[医药卫生—内科学]