促进白色脂肪棕色化的方法和可能的机制  

White adipose tissue browning: approaches and potential mechanism

作　　者：刘博轩 杨劲[2] 景志强[3] Liu Boxuan;Yang Jin;Jing Zhiqiang(School of International Pharmaceutical Business,China Pharmaceutical University,Nanjing 210000,China;School of Pharmacy,China Pharmaceutical University,Nanjing 210000,China;Research Center for Body Medicine Integration,China Pharmaceutical University,Nanjing 210000,China)

机构地区：[1]中国药科大学国际医药商学院,南京210000 [2]中国药科大学药学院,南京210000 [3]中国药科大学体药融合研究中心,南京210000

出　　处：《中华内分泌代谢杂志》2024年第5期440-445,共6页Chinese Journal of Endocrinology and Metabolism

基　　金：2021年教育部首批新文科实践项目(2021070044);2020年度江苏省体育局重大体育科研课题(ST202102)。

摘　　要：肥胖表现为脂肪组织中脂肪的过度堆积, 对健康带来严重威胁。目前, 促进白色脂肪棕色化成为对抗肥胖和代谢性疾病治疗的热点。本文从促进白色脂肪棕色化方法的角度进行探讨, 包括药物、局部热疗、运动和针灸, 总结了不同干预可能的机制和效果。旨在为应用白色脂肪棕色化减轻肥胖和改善代谢提供新思路。Obesity,characterized by the excess accumulation of fat in adipose tissue,poses a significant health risk.Presently,there is growing interest in promoting the browning of white adipose tissue as a strategy to address obesity and metabolic diseases.This article delves into various methods on white adipose tissue browning,encompassing pharmaceuticals,local thermotherapy,exercise,and acupuncture.It provides an overview of the potential mechanisms and effects of these interventions,aiming to offer fresh perspectives on leveraging white adipose tissue browning to mitigate obesity and improve metabolism.

关 键 词：白色脂肪组织 棕色化 减肥 药物 运动 局部热疗 针灸 

分 类 号：R589.2[医药卫生—内分泌]