猪源链球菌对β-内酰胺类抗生素的耐药性研究进展  

Research progress on drug resistance of Streptococcus suis to β-lactam antibiotics

作　　者：散仁 董鹏 朝博 红英 杨洺扬 Sanren;Dong Peng;Chaobo;Hongying;Yang Mingyang(Tongliao Agricultural and Animal Product Quality Safety Center,Inner Mongolia Tongliao 028000;Tongliao Animal Quarantine Technical Service Center,Inner Mongolia Tongliao 028000;Institute of Grassland Research,Chinese Academy of Agricultural Sciences,Inner Mongolia Hohhot 010010;Kulun Town Comprehensive Support and Technology Extension Center,Inner Mongolia Tongliao 028000;Liaoning Agricultural Development Service Center,Liaoning Shenyang 110164)

机构地区：[1]通辽市农畜产品质量安全中心,内蒙古通辽028000 [2]通辽市动物检疫技术服务中心,内蒙古通辽028000 [3]中国农业科学院草原研究所,内蒙古呼和浩特010010 [4]库伦镇综合保障和技术推广中心,内蒙古通辽028000 [5]辽宁省农业发展服务中心,辽宁沈阳110164

出　　处：《现代畜牧兽医》2024年第4期77-81,共5页Modern Journal of Animal Husbandry and Veterinary Medicine

摘　　要：猪链球菌病是生猪养殖中比较常见且危害较大的动物疫病,该病的病原是球菌科链球菌属的多种链球菌,其中猪链球菌2型是重要的人畜共患病原菌。β-内酰胺类抗生素一直是治疗猪链球菌病的首选药物,但受长期选用的影响,猪源链球菌对β-内酰胺类抗生素的耐药性逐渐增强,给猪链球菌病的临床治疗带来威胁。文章对猪链球菌病的流行性及病原特点、猪源链球菌对β-内酰胺类抗生素的耐药机制和耐药现状进行概述,以期为指导临床用药和新药研发提供参考。Streptococcussuis is a common and harmful animal disease in pig breeding.The pathogen of this disease is a variety of streptococci of Streptococcus of Coccidae,among which Streptococcus suis type 2 is an important zoonotic pathogen.β-lactam antibiotics have always been the first choice for the treatment of Streptococcussuis.However,due to the long-term selection,the resistance of Streptococcussuistoβ-lactam antibiotics has gradually increased,which poses a threat to the clinical treatment of Streptococcus suis.In the paper,the epidemic and pathogenic characteristics of Streptococcus suis,the resistance mechanism,and current situation of Streptococcus suis toβ-lactam antibiotics were summarized,in order to provide a reference for guiding clinical medication and new drug research and development.

关 键 词：猪源链球菌 Β-内酰胺类抗生素 耐药性 耐药机制 

分 类 号：S858.28[农业科学—临床兽医学]