赣州地区儿童下呼吸道感染病原体分布分析  

Distribution Analysis of Pathogens of Lower Respiratory Tract Infections in Children in Ganzhou

作　　者：郭诗君 GUO Shi-jun(Department of Pediatrics,Ganzhou Hospital of Guangdong Provincial People's Hospital/Ganzhou Municipal Hospital,Ganzhou 341000,China)

机构地区：[1]广东省人民医院赣州医院(赣州市立医院)儿科,江西赣州341000

出　　处：《实用临床医学（江西）》2024年第3期103-106,120,共5页Practical Clinical Medicine

摘　　要：目的 了解赣州地区0~14岁儿童下呼吸道感染病原学及流行病学特征。方法 回顾性分析2021年10月至2023年10月广东省人民医院赣州医院儿科收治的383例下呼吸道感染患儿,采用间接荧光免疫法检测患儿血清中呼吸道合胞病毒(RSV)、腺病毒(HAdV)、流感病毒A型(FluA)、流感病毒B型(FluB)、副流感病毒(HPIV)、肺炎支原体(MP)、肺炎衣原体(CP)、嗜肺军团菌(LP)、柯萨奇病毒A型(CoxA)、柯萨奇病毒B型(CoxB)、埃可病毒(ECHO)的IgM抗体,并对检测结果汇总分析。结果 383例下呼吸道感染患儿中阳性检出病例231例,阳性率60.3%,其中主要感染病原体为肺炎支原体;男性患儿和女性患儿比较,各病原检测阳性率差异无统计学意义(P>0.05);各季节中MP阳性检出率均排于首位,但差异无统计学意义(P>0.05),冬季FluA阳性检出率显著高于其他季节(P<0.05),夏冬季LP、FluB阳性检测率显著高于春、秋季(P<0.05)。不同年龄组呼吸道病原总阳性检出率有显著差异(P<0.05),其中学龄前组、学龄组中FluB阳性检出率显著高于婴幼儿组(P<0.05),学龄前组LP阳性检出率显著高于婴幼儿组(P<0.05)。结论 赣州地区下呼吸道感染患儿非典型病原菌MP、LP、CP感染率较高,主要为MP感染,全年易感,而流感病毒具有明显季节、年龄差异,学龄前、学龄儿童较婴幼儿流感病毒易感性高,冬季为高发季节。Objective To investigate the pathogenetic and epidemiologic characteristics of lower respiratory tract infections in children aged 0-14 years in Ganzhou.Methods 382 children with lower respiratory tract infections admitted to the Department of Pediatrics of our hospital from October 2021 to October 2023 were retrospectively analyzed;indirect fluorescence immunoassay was used to detect respiratory syncytial virus(RSV),adenovirus(HAdV),influenza virus type A(FluA),influenza virus type B(FluB),parainfluenza virus(HPIV),mycoplasma pneumoniae(MP),chlamydia pneumoniae(CP),legionella pneumophila(LP),Coxsackievirus A(CoxA),Coxsackievirus B(CoxB),and Echovirus(ECHO)IgM antibodies;the results of the tests were summarized and analyzed.Results Among the 383 children with lower respiratory tract infections,231 cases(60.3%)were reported positive,in which the main infectious agent was mycoplasma pneumoniae;the difference in the positivity rate of the detection of the various pathogens was not statistically significant when comparing male children and female children(P>0.05);the positive detection rate of MP ranked first in all seasons,but the difference was not statistically significant(P>0.05);the positive detection rate of FluA was significantly higher in winter than in other seasons(P<0.05);the positive detection rate of LP and FluB was significantly higher in summer and winter than in spring and fall(P<0.05).There was a significant difference in the total positive detection rate of respiratory pathogens in different age groups(P<0.05),with the positive detection rate of FluB in the preschool and school-age groups being significantly higher than that of the infant and toddler groups(P<0.05),and the positive detection rate of LP in the preschool group being significantly higher than that of the infant and toddler group(P<0.05).ConclusionThe findings suggest that children with lower respiratory tract infections in Ganzhouhave high rates of infection with atypical pathogens MP,LP,and CP,mainly MP infections,which are susceptibl

关 键 词：呼吸道感染 呼吸道病原体谱IgM抗体 儿童 赣州 江西 

分 类 号：R725.6[医药卫生—儿科] R446.6[医药卫生—临床医学]