置管溶栓联合多种腔内介入术治疗下肢动脉硬化闭塞症的效果  

Effect of Catheterization and Thrombolysis Combined with Various Endovascular Interventions Surgery in the Treatment of Arteriosclerosis Obliterans of Lower Limbs

作　　者：黄扬杰 王亮[1] 何天敏 罗滨 HUANG Yangjie;WANG Liang;HE Tianmin;LUO Bin(The Second Hospital of Sanming City,Yong’an 366000,China;不详)

机构地区：[1]三明市第二医院,福建永安366000

出　　处：《中外医学研究》2024年第16期114-118,共5页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探究置管溶栓联合多种腔内介入术治疗下肢动脉硬化闭塞症的效果。方法:回顾性选取2015年5月—2023年5月三明市第二医院收治的90例下肢动脉硬化闭塞症患者。根据治疗方法的不同将其分为参照组和试验组,各45例。参照组给予多种腔内介入术治疗,试验组给予置管溶栓联合多种腔内介入术治疗。比较两组治疗前、治疗后1个月相关指标、足背动脉血流动力学、神经传导速度、疼痛程度及围手术期指标、手术疗效。结果:治疗后1个月,两组踝肱指数、足趾血氧饱和度及足部皮温、血管内径及血流量、下肢感觉及运动神经传导速度均升高,视觉模拟评分法(VAS)评分、血流峰速降低,差异有统计学意义(P<0.05)。两组踝肱指数、足趾血氧饱和度及足部皮温、血管内径、血流峰速及血流量、下肢感觉、运动神经传导速度及VAS评分比较,差异无统计学意义(P>0.05)。试验组手术时间与住院时间均短于参照组,差异有统计学意义(P<0.05)。试验组血管开通率高于参照组,支架植入率及截肢率均低于参照组,差异有统计学意义(P<0.05)。结论:下肢动脉硬化闭塞症采用置管溶栓联合多种腔内介入术可有效提高患者下肢神经传导速度,优化足背动脉血流动力学,同时能减少支架植入,降低截肢风险,缩短康复周期,其整体疗效更显著。Objective:To explore the effect of catheterization and thrombolysis combined with various intracavitary interventions surgery in the treatment of arteriosclerosis obliterans of lower limbs.Method:Ninety patients with lower extremity arteriosclerosis obliterans admitted to the Second Hospital of Sanming City from May 2015 to May 2023 were retrospectively selected.According to the different treatment methods,they were divided into reference group and experimental group,45 cases in each group.The reference group was treated with various endovascular interventions surgery,and the experimental group was treated with catheter thrombolysis combined with various endovascular interventions surgery.The relevant indexes,hemodynamics of dorsalis pedis,nerve conduction velocity,pain degree before and 1 month after treatment,perioperative indexes,and operative effect were compared between the two groups.Result:At 1 month after treatment,ankle-brachial index,toe blood oxygen saturation,foot skin temperature,blood vessel diameter and blood flow,sensory and motor nerve conduction velocity of lower limbs were all increased in the two groups,while visual analogue scale(VAS)and peak blood flow velocity score were decreased,the differences were statistically significant(P<0.05).There were no significant differences in ankle-brachial index,toe blood oxygen saturation,foot skin temperature,vascular diameter,peak blood flow velocity and blood flow,sensory and motor nerve conduction velocity of lower limbs,VAS score between the two groups(P>0.05).The operation time and hospitalization time of experimental group were shorter than those of reference group,and the differences were statistically significant(P<0.05).The vascular opening rate of experimental group was higher than that of reference group,and the stent implantation rate and amputation rate were lower than those of reference group,the differences were statistically significant(P<0.05).Conclusion:In patients with lower extremity arteriosclerosis obliterans,catheterization and thro

关 键 词：置管溶栓 多种腔内介入术 下肢动脉硬化闭塞症 临床疗效 

分 类 号：R654.4[医药卫生—外科学]