4种生物敷料治疗深Ⅱ度烧伤患者的临床效果对比研究  

Effect of four biological skin dressings for treating patients with deepⅡdegree burn wounds

作　　者：朱国强 李苗苗 李雨洋 Zhu Guoqiang;Li Miaomiao;Li Yuyang(Department of Burn and Plastic,the 985th Hospital of the People′s Liberation Army Joint Logistics Support Force,Taiyuan 030001,China)

机构地区：[1]联勤保障部队第985医院烧伤整形科,太原030001

出　　处：《山西医药杂志》2024年第9期643-646,共4页Shanxi Medical Journal

基　　金：军队医学科技青年培育计划拔尖项目(19QNP067)。

摘　　要：目的比较临床上常用的4种生物敷料治疗深Ⅱ度烧伤患者的临床效果。方法选取2012年1月至2022年1月期间在我院接受治疗的深Ⅱ度烧伤患者210例作为研究对象,随机分为5组,每组42例,分别使用泡沫敷料、负压引流装置、纳米银、辐照猪皮为试验组,对照组使用磺胺嘧啶银,观察对比各组患者创面换药次数,创面愈合时间,二次创伤评分,疼痛评分,自体植皮手术发生率及瘢痕情况。结果4种生物敷料创面换药次数均低于对照组(P<0.05),泡沫敷料、负压引流装置创面愈合时间明显缩短(P<0.05),4种生物敷料疼痛评分低于对照组(P<0.05),泡沫敷料、负压引流装置二次创伤评分、二次植皮手术发生率与瘢痕情况低于对照组(P<0.05)。结论4种生物敷料治疗深Ⅱ度烧伤较传统治疗有明显优势,泡沫敷料、负压引流装置可有效的促进深Ⅱ度烧伤创面的愈合,减少创面感染率。Objective To compare the clinical effects of four biological dressings to treat patients with deepⅡdegree burn wounds.Methods Two hundred and ten patients with deepⅡdegree burn wounds who were treated in our hospital from January 2012 to January 2022 were selected as the research objects and randomly divided into 5 groups.Forty-two patients were in each group.Foam dressing,negative pressure device,nano silver,and irradiated pig skin were respectively used as the test group,and silver sulfadiazine was used as the control group.The frequency of dressing changes,wound healing time,secondary trauma score,pain score,incidence of autologous skin grafting,and scar in each group were observed.Results The number of dressing changes on the four biological dressing wounds was lower than that in the control group(P<0.05).The wound healing time of foam dressing and negative pressure drainage device was significantly shortened(P<0.05).The four test groups′pain scores were lower than those of the control group(P<0.05).The secondary trauma score,the incidence of secondary skin grafting,and the scar in the foam dressing and negative pressure device groups were significantly better than those of the control group(P<0.05).Conclusion Four biological dressings have obvious advantages over traditional treatments in the treatment of deepⅡdegree burn wounds.Foam dressing and negative pressure devices can effectively promote the healing of deepⅡdegree burn wounds and reduce the wound infection rate.

关 键 词：烧伤 生物敷料 感染 

分 类 号：R644[医药卫生—外科学]