个性化营养干预对老年慢性阻塞性肺疾病病人肺功能及免疫状态的影响  

Effects of personalized nutrition intervention on lung function and immune status in elderly patients with chronic obstructive pulmonary disease

作　　者：马升军[1] 郑艾波 沈奕播[1] 古丽 孙楷[1] 黄丹 MA Shengjun;ZHENG Aibo;SHEN Yibo;GU Li;SUN Kai;HUANG Dan(Department of Respiratory and Critical Care Medicine,the Fourth People’s Hospital of Zigong,Ziogng 643000,China;Department of Nutrition,the Fourth People’s Hospital of Zigong,Ziogng 643000,China)

机构地区：[1]自贡市第四人民医院呼吸与危重症医学科,四川省自贡市643000 [2]自贡市第四人民医院营养科,四川省自贡市643000

出　　处：《实用老年医学》2024年第7期683-687,共5页Practical Geriatrics

基　　金：自贡市卫生健康科研课题(21yb036);自贡市第四人民医院院内培育项目(202108)。

摘　　要：目的 探讨个性化营养干预对存在营养不良风险的老年COPD病人肺功能和免疫状态的影响。方法 选取128例经营养风险筛查2002(NRS2002)量表筛查存在营养不良风险的老年COPD病人,按随机数表法分为个性化营养干预组和对照组,每组64例。个性化营养干预组接受个体化营养治疗,对照组接受常规营养指导,3个月后比较2组营养状态指标、肺功能指标、运动耐量指标及免疫状态指标的变化。结果 治疗后,个体化营养干预组的营养状态、肺功能、运动耐量及免疫状态指标均较治疗前明显改善(P<0.05),且明显优于对照组(P<0.05)。对照组治疗后营养指标和免疫指标较治疗前明显改善(P<0.05),但肺功能和运动耐量指标治疗前后差异无统计学意义(P>0.05)。结论 对存在营养不良风险的老年COPD病人实施个性化营养干预可改善营养状态、提升肺功能及运动耐量,恢复其免疫状态。Objective To explore the effects of personalized nutrition intervention on lung function and immune status in the elderly patients with chronic obstructive pulmonary disease(COPD)and malnutrition risk.Methods A total of 128 elderly COPD patients with malnutrition risk screened by Nutrition Risk Screening 2002(NRS 2002)score were divided into the personalized nutrition intervention group and the control group according to random number table method,with 64 cases in each group.The personalized nutrition intervention group was given individualized nutrition treatment,and the control group was given routine nutrition guidance.The indexes of nutritional status,lung function,exercise tolerance and immune status were observed and compared after 3 months of treatment.Results After treatment,the indexes of nutritional status,lung function,exercise tolerance and immune status in the individualized nutrition intervention group were all significantly improved compared with those before treatment(P<0.05),and showed significant difference with those in the control group(P<0.05).The indexes of nutritional status and immune status in the control group were significantly improved after treatment(P<0.05),while there were no significant difference in the lung function and exercise tolerance(P>0.05).Conclusions Individualized nutritional intervention can improve nutritional status,enhance lung function and exercise tolerance,and restore immune status in the elderly COPD patients with the risk of malnutrition.

关 键 词：个性化营养干预 营养不良 慢性阻塞性肺疾病 肺功能 免疫状态 

分 类 号：R563[医药卫生—呼吸系统]