晚期心力衰竭患者院内肺部感染的影响因素分析  

The influencing factors of hospital acquired pulmonary infection in patients with advanced heart failure

作　　者：吴国华[1] 钱琳艳[1] 赵嫣[1] 王成[1] 吴观军 Wu Guohua

机构地区：[1]浙江省人民医院(杭州医学院附属人民医院),310014

出　　处：《浙江临床医学》2024年第6期814-816,共3页Zhejiang Clinical Medical Journal

基　　金：浙江省中医药科技计划项目(2022ZA022)。

摘　　要：目的分析晚期心力衰竭患者发生院内肺部感染的影响因素,并评估这些影响因素的诊断价值。方法纳入晚期心力衰竭患者485例,根据患者入院期间是否发生肺部感染进行分组。收集患者入院期间一般资料和实验室及影像学检查。比较两组患者的基线资料。采用单因素及多因素Logistic回归分析明确晚期心力衰竭患者肺部感染的影响因素,采用ROC曲线评估其诊断价值。结论相较于无肺部感染的心力衰竭患者,肺部感染的心力衰竭患者BNP和NYHA分级增加,HDL-C和LVEF水平降低(P<0.05)。单因素及多因素Logistic回归分析表明,HDL-C、LVEF、BNP、NYHA是晚期心力衰竭患者发生院内肺部感染的独立影响因素。ROC曲线显示,HDL-C联合LVEF、BNP、NYHA对晚期心力衰竭患者院内肺部感染的发生具有一定的诊断价值(P<0.001)。结论HDL-C、LVEF、BNP、NYHA是晚期心力衰竭患者肺部感染的独立影响因素。Objective To identify the influencing factors of nosocomial pulmonary infection in patients with advanced heart failure and to evaluate the diagnostic value of these influencing factors.Methods The study included 485 patients with advanced heart failure who were grouped according to whether they developed lung infection during admission.General clinical data,laboratory and imaging results were collected during admission.Baseline data were compared between the two groups.Univariate and multivariate Logistic regression analysis were used to identify the influencing factors of pulmonary infection in patients with advanced heart failure,and ROC curve was used to evaluate its diagnostic value.Conclusion BNP and NYHA levels increased and HDL-C and LVEF levels decreased in patients with heart failure with lung infection compared with patients without lung infection(P<0.05).Univariate and multivariate Logistic regression analysis showed that HDL-C,LVEF,BNP and NYHA were independent influencing factors of nosocomial pulmonary infection in patients with advanced heart failure.ROC curve showed that combined HDL-C,LVEF,BNP and NYHA had certain diagnostic value in the occurrence of nososoial pulmonary infection in patients with advanced heart failure(P<0.001).Conclusion HDL-C,LVEF,BNP and NYHA are independent factors of pulmonary infection in patients with advanced heart failure.

关 键 词：心力衰竭 肺部感染 影响因素 

分 类 号：R541.6[医药卫生—心血管疾病]