胃宁散治疗慢性胃炎脾胃气虚证的疗效观察  

作　　者：许宝才 徐鑫陵 陈伟 陈凯 

机构地区：[1]浙江省衢州市中医医院,324002

出　　处：《浙江临床医学》2024年第6期879-880,883,共3页Zhejiang Clinical Medical Journal

基　　金：浙江省中医药科技计划项目(2020ZB289,2021ZB324);浙江中医药大学校级科研项目附属医院科研专项(2021FSYYZZ18,2021FSYYZQ14);衢州市科技攻关项目第二批中医药专项(2022K113,2022K127)。

摘　　要：目的观察胃宁散治疗慢性胃炎(CG)脾胃气虚证的疗效。方法选取CG脾胃气虚证患者96例,随机分为观察组(48例)与对照组(48例)。观察组予胃宁散治疗,对照组予雷贝拉唑、莫沙必利治疗,疗程均为4周,比较两组疗效。结果治疗后,观察组中医症候疗效(95.7%)优于对照组(83.0%)(P<0.05),观察组症状积分高于对照组(P<0.05),观察组胃镜病理组织学疗效有效率(84.8%)高于对照组(63.8%),且观察组病理组织学疗效优于对照组(P<0.05)。治疗后两组胃黏膜损伤指标G17、PGI及PGR较治疗前均有所升高,且两组比较差异有统计学意义(P<0.05)。结论胃宁散是治疗CG脾胃气虚证的安全有效方剂,值得临床推广应用。Objective To observe the efficacy of WeiNing powder in treating chronic gastritis(CG)of spleen-stomach Qi deficiency syndrome.Methods 96 cases of CG spleen-stomach qi deficiency syndrome were randomly divided into observation group(48 cases)and control group(48 cases).The observation group was treated with WeiNing powder,while the control group was treated with rabeprazole and mosapride.The course of treatment was 4 weeks.Results After treatment,the curative effect of TCM symptoms in the observation group(95.7%)was better than that in the control group(83.0%)(P<0.05),and the symptom integral in the observation group was higher than that in the control group(P<0.05),the effective rate(84.8%)in the observation group was higher than that(63.8%)in the control group,and the effect of the Observation Group was better than that of the control group(P<0.05).G17,PGI and PGR were increased after treatment in both groups,and there was significant difference between the two groups(P<0.05).Conclusion WeiNing powder is a safe and effective prescription for the treatment of spleen-stomach Qi deficiency syndrome of CG,which is worthy of clinical application.

关 键 词：慢性胃炎 脾胃气虚 胃宁散 

分 类 号：R259[医药卫生—中西医结合]