耳尖刺血技术治疗火毒蕴结型早期低位感染性肛周脓肿的效果  

Clinical efficacy of ear-tip blood-prick technique in treating early low-grade infected perianal abscess of fire poison accumulation

作　　者：郑海霞[1] 潘铨[1] 陈文捷[1] ZHENG Hai-xia;PAN Quan;CHEN Wen-jie(Lishui Traditional Chinese Medicine Hospital,Lishui,Zhejiang323000,China)

机构地区：[1]丽水市中医院外科,浙江丽水323000

出　　处：《中华医院感染学杂志》2024年第11期1706-1710,共5页Chinese Journal of Nosocomiology

基　　金：浙江省中医药科技计划科研基金资助项目(2021ZB336)。

摘　　要：目的 研究耳尖刺血技术治疗火毒蕴结型早期低位感染性肛周脓肿的效果.方法 选择2021年1月-2022年12月丽水市中医院收治的火毒蕴结型早期低位感染性肛周脓肿患者为研究对象,随机分为常规治疗的常规组(30例)和联合耳尖刺血技术治疗的耳尖刺血组(30例);统计两组治疗2周后的临床疗效及治疗期间不良反应发生情况,比较两组治疗前和治疗2周后血清细胞因子、炎性因子水平及创面血氧供应情况、水肿情况、症状与体征评分.结果 治疗2周后,耳尖刺血组总疗效优于高于常规组(P=0.039);治疗2周后两组血清酸性成纤维细胞生长因子(aFGF)、碱性成纤维细胞生长因子(bFGF)、转化生长因子-β(TGF-β)水平及创面血流量、经皮氧分压与治疗前比较均升高,且耳尖刺血组高于常规组(P<0.05);两组血清激活素A(ACTA)、超敏C-反应蛋白(hs-CRP)、肿瘤坏死因子-α(TNF-α)、白细胞介素-10(IL-10)及前列腺素E2(PGE2)水平、创面水肿、肛门疼痛、全身症状、肿块大小、肿块质地评分与治疗前比较,均降低,耳尖刺血组低于常规组(P<0.05);治疗期间,两组均未发生严重不良反应;耳尖刺血组发生2例耳尖红肿,未经处理隔日后自行消肿,常规组发生1例恶心,饮用温水后症状消失.结论 耳尖刺血技术可有效改善火毒蕴结型早期低位感染性肛周脓肿患者血清细胞因子水平、创面血氧供应情况及症状与体征,降低炎性因子水平,有助于创面水肿消除及愈合,疗效和安全性较好.OBJECTIVE To investigate the clinical efficacy of ear-tip blood-prick technique in treating early lowgrade infected perianal abscess of fire poison accumulation type.METHODS From Jan.2021 to Dec.2022,patients with early low-grade infectious perianal abscess of fire and toxicity accumulated in Lishui traditional Chinese medicine hospital were selected and divided into the conventional group(30 cases)and the ear-tip blood-prick group(30 cases)combined with ear-tip blood-prick technique by random number table method.Both groups were treated for 2 weeks.The clinical efficacy of the two groups after 2 weeks of treatment and the occurrence of adverse reactions during treatment were analyzed,and the levels of serum cytokines,inflammatory factors,wound blood oxygen supply,edema,and symptom and sign scores were compared between the two groups before and after 2 weeks of treatment.RESULTS After 2 weeks of treatment,the total efficacy of the ear-tip blood-prick group was significantly higher than that of the conventional group(P=0.039).After 2 weeks of treatment,the serum levels of acid fibroblast growth factor(aFGF),basic fibroblast growth factor(bFGF),transforming growth factor-β(TGF-β),wound blood flow and percutaneous partial oxygen pressure in 2 groups were increased compared with those before treatment,and those in the ear-tip blood-prick group were higher than those in the conventional group(P<0.05).The levels of serum activin A(ACTA),hypersensitive C-reactive protein(hs-CRP),tumor necrosis factor-α(TNF-α),interleukin-10(IL-10)and prostaglandin E2(PGE2),wound edema,anal pain,systemic symptoms,mass size and mass texture in two groups were decreased compared with those before treatment,and those in the ear-tip blood-prick group was lower than the conventional group(P<0.05).No serious adverse events occurred in both groups during treatment.In the ear-tip blood-prick group,2 cases of ear tip redness and swelling were self-alleviated after the next day without treatment.In the conventional group,1 case of nausea occur

关 键 词：早期低位感染性肛周脓肿 低位感染 肛周脓肿 火毒蕴结型 早期 耳尖刺血技术 甲硝唑 左氧氟沙星 临床疗效 

分 类 号：R266[医药卫生—中医外科学]