益气养阴方灌肠治疗晚期癌症肠梗阻临床研究  

Clinical Study on Enema with Yiqi Yangyin Prescription for Intestinal Obstruction with Advanced Cancer

作　　者：徐美连 姜美青[2] 郑玉红 XU Meilian;JIANG Meiqing;ZHENG Yuhong(School of Nursing,Zhejiang Chinese Medical University,Hangzhou Zhejiang 310053,China;People's Hospital of Quzhou,Quzhou Zhejiang 324000,China)

机构地区：[1]浙江中医药大学护理学院,浙江杭州310053 [2]衢州市人民医院,浙江衢州324000

出　　处：《新中医》2024年第11期161-165,共5页New Chinese Medicine

摘　　要：目的:观察益气养阴方灌肠治疗晚期癌症患者肠梗阻的临床疗效。方法:选择92例晚期癌症肠梗阻患者,按随机数字表法分为联合组和西医组各46例。西医组接受常规西医治疗,联合组在西医组基础上接受益气养阴方灌肠治疗,连续治疗5 d。比较2组临床疗效、症状缓解时间,并比较2组治疗前后中医症状评分、胃肠激素水平。结果:联合组总有效率89.13%,高于西医组71.74%(P<0.05)。治疗后,2组排气排便停止、腹痛阵作、胀满拒按、恶心呕吐等症状评分均降低(P<0.05),且联合组低于西医组(P<0.05)。联合组排便恢复时间、肠鸣音恢复时间、腹胀腹痛缓解时间均短于西医组(P<0.05)。治疗后,2组血清二胺氧化酶(DAO)、胃泌素(GAS)水平均降低(P<0.05),且联合组低于西医组(P<0.05);2组胃动素(MOT)水平均升高(P<0.05),且联合组高于西医组(P<0.05)。结论:益气养阴方灌肠可有效缓解晚期癌症患者肠梗阻的临床症状,改善胃肠功能,调节胃肠激素水平。Objective:To observe the clinical effect of enema with Yiqi Yangyin Prescription on intestinal obstruction in patients with advanced cancer.Methods:A total of 92 cases of patients with advanced cancer complicated with intestinal obstruction were selected and divided into the combination group and the western medicine group according to the random number table method,with 46 cases in each group.The western medicine group was given routine western medicine treatment,and the combination group was additionally treated with enema with Yiqi Yangyin Prescription based on the treatment of the western medicine group.Both groups were treated for five days.The clinical effects and symptom relief time were compared between the two groups;symptom scores and gastrointestinal hormone levels were compared before and after treatment between the two groups.Results:The total effective rate was 89.13%in the combination group,higher than that of 71.74%in the western medicine group(P<0.05).After treatment,the scores of symptoms such as stop of exhaust and defecation,bouts of abdominal pain,distention and fullness which refuse pressure,nausea and vomiting were all decreased in the two groups(P<0.05),and the above scores in the combination group were lower than those in the western medicine group(P<0.05).The recovery time of defecation and bowel sound and the relief time of abdominal distension in the combination group were shorter than those in the western medicine group(P<0.05).After treatment,the levels of diamine oxidase(DAO)and gastrin(GAS)in serum in the two groups were decreased(P<0.05),and the levels in the combination group were lower than those in the western medicine group(P<0.05);motilin(MOT)levels in the two groups were increased(P<0.05),and the level in the combination group was higher than that in the western medicine group(P<0.05).Conclusion:Enema with Yiqi Yangyin Prescription can effectively relieve the clinical symptoms of intestinal obstruction in patients with advanced cancer,improve their gastrointestinal function

关 键 词：晚期癌症 肠梗阻 益气养阴方 中药灌肠 胃肠激素 

分 类 号：R273[医药卫生—中西医结合] R730.5[医药卫生—中医肿瘤科]