雌二醇凝胶联合米索前列醇在绝经后妇女取环术中的临床效果分析  

Analysis of the Clinical Effect of Estradiol Gel Combined with Misoprostol in Postmenopausal Women Undergoing IUD Extraction

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作  者:池雅珍 CHI Yazhen(Department of Gynecological Protection,Nanping Jianyang District Maternal and Child Health Hospital,Nanping,Fujian Province,354200 China)

机构地区:[1]南平市建阳区妇幼保健院妇保科,福建南平354200

出  处:《中外医疗》2024年第15期82-85,共4页China & Foreign Medical Treatment

摘  要:目的 探讨雌二醇凝胶联合米索前列醇在绝经后妇女取环术中的临床效果。方法 随机选取2022年6月—2023年6月南平市建阳区妇幼保健院行取环术的100例绝经后妇女为研究对象,按照治疗方案分为两组,每组50例。对照组行取环术前予以米索前列醇处理,观察组给予雌二醇凝胶+米索前列醇方案预处理,对比两组宫颈软化效果、手术成功率、手术相关指标以及不良反应发生状况。结果 观察组宫颈软化率、手术成功率均高于对照组,差异有统计学意义(P均<0.05)。观察组取环时间及取环时疼痛评分均优于对照组,差异有统计学意义(P均<0.05)。两组术中出血量比较,差异无统计学意义(P>0.05)。两组患者的不良反应发生率比较(2.00%vs 6.00%),差异无统计学意义(χ^(2)=0.260,P=0.609)。结论 雌二醇凝胶与米索前列醇联合用于绝经后妇女取环术的预处理,能够明显提升宫颈软化效果,减少取环手术时间,提高手术成功率,减轻取环时患者的疼痛状况,且安全性较高。Objective To study the clinical effect of estradiol gel combined with misoprostol in postmenopausal women undergoing intra-uterine device(IUD)extraction.Methods One hundred cases of postmenopausal women who underwent IUD in Nanping Jianyang District Maternal and Child Health Hospital from June 2022 to June 2023 were ran⁃domly selected as study subjects,and were divided into two groups according to the treatment plan,with 50 cases in each group.The control group was treated with misoprostol before IUD extraction,and the observation group was pretreated with estradiol gel+misoprostol.The cervical softening effect,surgical success rate,surgical related indexes and the occurrence of adverse reactions were compared between the two groups.Results The cervical softening rate and surgical success rate of the observation group were higher than those of the control group,and the differences were statistically significant(all P<0.05).The time of IUD removal and the pain score during IUD removal were better in the observation group than those in the control group,and the differences were statistically significant(both P<0.05).The difference in intraoperative bleeding between the two groups was not statistically significant(P>0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(2.00%vs 6.00%)(χ^(2)=0.260,P=0.609).Conclusion The combination of estradiol gel and misoprostol for the pretreatment of IUD extraction in postmenopausal women can significantly improve the effect of cervical softening,reduce the time of IUD extraction,improve the success rate of the procedure,reduce the pain condition of the patients during the IUD extraction,and have a high degree of safety.

关 键 词:绝经后妇女取环术 雌二醇凝胶 米索前列醇 宫颈软化效果 疼痛状况 

分 类 号:R5[医药卫生—内科学]

 

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