多囊卵巢综合征内分泌异常的诊治  

Diagnosis and treatment of endocrine disorders in polycystic ovary syndrome.

作　　者：朱琴玲[1] 孙贇[1] ZHU Qin-ling;SUN Yun(Center for Reproductive Medicine,Shang-hai Key Laboratory for Assisted Reproduction and Reproductive Genetics,Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai 200135,China)

机构地区：[1]上海交通大学医学院附属仁济医院生殖医学中心、上海市辅助生殖与优生重点实验室,上海200135

出　　处：《中国实用妇科与产科杂志》2024年第6期608-614,共7页Chinese Journal of Practical Gynecology and Obstetrics

基　　金：国家自然科学基金(82130046,82320108009);上海交通大学医学院高水平创新团队激励计划-协同创新团队(SHSMU-ZLCX20210200,SHSMU-ZLCX20210201);上海市加强公共卫生体系建设三年行动计划(GWVI-11.1-36);上海市重中之重研究中心建设项目(2023ZZ02002)。

摘　　要：多囊卵巢综合征(polycystic ovary syndrome,PCOS)是女性最常见的、复杂的生殖内分泌紊乱疾病。PCOS患者下丘脑-垂体-卵巢轴功能紊乱,常伴随高雄激素血症及高胰岛素血症等内分泌异常。精准评估PCOS内分泌状态是早发现、早诊断及早治疗相关异常的重要手段。针对内分泌紊乱及女性生育需求等,PCOS患者主要以个体化治疗为主,且该病贯穿于女性全生命周期,需制定系统的、长期的全程管理计划。Polycystic ovary syndrome(PCOS)is the most common and complex disease in women of re⁃productive-age.PCOS suffered from hypothalamicpituitary-ovarian axis dysfunction,accompanied by endocrine disorders with hyperandrogenemism and hyerinsulinism and so on.Accurate assessment endo⁃crine status is a key step for early detection,early di⁃agnosis and early treatment for women affected with PCOS.Individualized treatment is mainly designed to target the endocrine disorders and fertility requirement for PCOS.PCOS is a disease across the life cycle of the affected women,a systemic and long-term management plan needs to be formulated.

关 键 词：多囊卵巢综合征 内分泌异常 高雄激素血症 

分 类 号：R711.6[医药卫生—妇产科学]