子宫内膜异位症患者冻融胚胎移植内膜准备方案的研究进展  

Research progress on endometrial preparation for frozen-thawed embryo transfer cycles in patients with endometriosis

作　　者：赵雨欣 张婕[1] 蒋春艳[1] 刘嘉茵[1] Zhao Yuxin;Zhang Jie;Jiang Chunyan;Liu Jiayin(Clinical Center of Reproductive Medicine,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学第一附属医院临床生殖医学中心,南京210029

出　　处：《中华生殖与避孕杂志》2024年第5期522-525,共4页Chinese Journal of Reproduction and Contraception

基　　金：国家重点研发计划(2017YFC1001303);国家自然科学基金(81730041)。

摘　　要：子宫内膜异位症(endometriosis,EMS)是育龄女性的常见疾病,也是人类辅助生殖技术的常用指征之一。随着玻璃化冷冻技术的发展,冻融胚胎移植(frozen-thawed embryo transfer,FET)成为体外受精技术的重要组成部分。影响FET成功的因素包括胚胎质量、子宫内膜容受性及胚胎与内膜的同步性。其中内膜准备是胚胎着床和活产的关键步骤。EMS被认为是影响子宫内膜容受性的重要病因。目前针对EMS患者FET内膜准备方案研究较少并存在争议。本文通过分析现有文献,对EMS患者FET内膜准备方案的妊娠结局、母婴并发症进行综述,为临床决策提供参考。Endometriosis(EMS)is a common disease afflicting females of reproductive age and a common indication of human assisted reproductive technology.With the development of technology of vitrification,frozen-thawed embryo transfer(FET)has become an essential component of in vitro fertilization.The factors that affect the success of FET include embryo quality,endometrial receptivity,and synchronization between embry and endometrium.The preparation of the endometrium is a key step in embryo implantation and live birth.EMS is considered as an important cause affecting endometrial receptivity.At present,there are few studies and controversies on the FET endometrial preparation plan for EMS patients.This article reviews the pregnancy outcomes and maternal infant complications of FET endometrial preparation in EMS patients by analyzing existing literature,providing reference for clinical decision-making.

关 键 词：子宫内膜异位症 妊娠结局 冻融胚胎移植 子宫内膜准备 

分 类 号：R714.8[医药卫生—妇产科学]