手性光场及其在分子手性探测方面的近期研究进展(特邀)  

Chiral Light Field and Its Recent Research Progress in Molecular Chirality Detection(Invited)

作　　者：穆晓伟 叶冲 张向东[1] Mu Xiaowei;Ye Chong;Zhang Xiangdong(School of Physics,Beijing Institute of Technology,Beijing 100081,China)

机构地区：[1]北京理工大学物理学院,北京100081

出　　处：《光学学报》2024年第10期247-263,共17页Acta Optica Sinica

基　　金：国家自然科学基金(12105011)。

摘　　要：手性分子在自然界中广泛存在,探究手性分子的光学响应是一个热点问题。产生手性响应往往需要手性的光场,光场的手性很大程度上影响着手性介质的光学响应强度。因此,如何增强普通光场的手性特性是手性研究中的一个核心问题。通过合理设计微纳结构可以增强局域电磁场,使得分子与光场的相互作用增强,从而使得提高手性探测能力成为可能。本文主要围绕微纳结构超手性场的调制和在手性表征中的应用展开介绍,并聚焦近期的研究进展。一方面,本文介绍了基于微纳结构增强的超手性场;另一方面,介绍了基于超手性热点的手性分子超灵敏检测以及基于矢量外点的超手性场增强手性光力应用。除此之外,本文还介绍了合成手性光这一新型手性光场的相关研究,从手性光场的空间特征、光与分子相互作用和手性分子表征等方面比较手性光的差异。为更好地理解光场的手性以及分子手性光学响应的来源提供帮助,并且为进一步调控光场手性和利用它们实现更快、更准的手性分子表征提供新的思路。Significance Chirality is a property of an object that cannot be superimposed on its mirror image by translation or rotation operations.The two enantiomers of chiral molecules have the same physical properties but completely different chemical properties.Therefore,effective detection and characterization of chiral molecules are crucial for such fields as pharmaceuticals and biochemistry.Chiral objects exhibit optical activity,and the optical chirality response generated during the interaction with other chiral objects provides a basic strategy for effective enantiomer identification.The light field plays a vital role in the detection of chiral molecules,and according to Curie s asymmetry principle,the chiral response often requires a chiral light field.The light field chirality greatly affects the optical response intensity of chiral media.Therefore,how to enhance the chirality of ordinary light fields is a core issue in chirality research.The circularly polarized light field is the most common type of chiral light,playing an important part in chiral responses such as optical rotation,circular dichroism,and Raman optical activity.However,the chiral response generated by circularly polarized light fields is often weak,which greatly affects the ability of these methods to detect molecular chirality.Therefore,many other optical fields have been proposed,such as superchiral field,optical field with orbital angular momentum,and synthetic chiral light.Progress Currently,extensive theoretical and experimental research has been conducted on the regulation of chiral light fields and their ultra-sensitive detection with the assistance of artificial nanostructures.After the concept of optical chirality(C)was proposed,its physical meaning was improved by Tang and Cohen.By employing the expression of optical chirality,when the optical chirality of a certain light field is greater than that of circularly polarized light,it is called superchiral field.When chiral structures are adopted for chiral detection,the chiral signals of

关 键 词：微纳光学 超手性场 合成手性光 

分 类 号：O436[机械工程—光学工程]