UV,five wavelengths fusion and electrochemical fingerprints combined with antioxidant activity for quality control of antiviral mixture  

作　　者：Kaining Zhou Zini Tang Guoxiang Sun Ping Guo Lili Lan 

机构地区：[1]College of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China

出　　处：《Asian Journal of Traditional Medicines》2024年第3期119-136,151,共19页亚洲传统医药（英文）

基　　金：This study was supported by the National Natural Science Foundation of China(No.81573586).

摘　　要：Aiming to ensure the consistency of quality control of Traditional Chinese Medicines(TCMs),a combination method of high-performance liquid chromatography(HPLC),ultraviolet(UV),electrochemical(EC)was developed in this study to comprehensively evaluate the quality of Antiviral Mixture(AM),and Comprehensive Linear Quantification Fingerprint Method(CLQFM)was used to process the data.Quantitative analysis of three active substances in TCM was conducted.A fivewavelength fusion fingerprint(FWFF)was developed,using second-order derivatives of UV spectral data to differentiate sample levels effectively.The combination of HPLC and UV spectrophotometry,along with electrochemical fingerprinting(ECFP),successfully evaluated total active substances.Ultimately,a multidimensional profiling analytical system for TCM was developed.

关 键 词：TCM antiviral mixture five-wavelength fusion fingerprint(FWFF) Comprehensive Linear Quantification Fingerprint Method(CLQFM) quantization fingerprint antioxidant activity profilling 

分 类 号：R284[医药卫生—中药学]