灵芝活性成分抗肿瘤机制研究进展  

Progress on anti-tumor mechanisms of Ganoderma lucidum active ingredients

作　　者：吕俞娇 周姝婷 王丽娜 沈明妹 刘永超 LV Yujiao;ZHOU Shuting;WANG Lina;SHEN Mingmei;LIU Yongchao(Medical Technology College of Beihua University,Jilin 132013,Jilin,China;Stomatology of Beihua University,Jilin 132013,Jilin,China)

机构地区：[1]北华大学医学技术学院,吉林吉林132013 [2]北华大学口腔医学院,吉林吉林132013

出　　处：《中国临床药理学与治疗学》2024年第8期947-954,共8页Chinese Journal of Clinical Pharmacology and Therapeutics

基　　金：吉林省科技发展计划项目(20220402072GH)。

摘　　要：恶性肿瘤是我国慢性病死亡的主要原因之一,其发病率和死亡率呈现逐年增加趋势。恶性肿瘤的晚期非手术治疗是改善患者预后,提高其生存质量的重要手段。传统中药灵芝具有抗肿瘤作用,在多种恶性肿瘤治疗中发挥作用。本文就近五年来国内外应用灵芝活性成分针对肿瘤的作用研究进行系统综述,探讨灵芝活性成分抗肿瘤的作用机制,为灵芝活性成分应用于临床奠定理论基础。Malignant tumors are one of the main causes of death from chronic diseases in China,and their incidence and mortality rates show an increasing trend year by year.Advanced non-surgical treatment of malignant tumors is an important means of improving patients'prognosis and enhancing their quality of life.The traditional Chinese medicine Ganoderma lucidum has anti-tumor effects and plays a role in the treatment of many malignant tumors.In this paper,a systematic review of the effects of Ganoderma lucidum active ingredients on tumors has been conducted at home and abroad in the past five years to explore the anti-tumor mechanism of Ganoderma lucidum active ingredients and to lay a theoretical foundation for the application of Ganoderma lucidum active ingredients in clinical practice.

关 键 词：灵芝 灵芝多糖 灵芝三萜 灵芝酸 抗肿瘤 

分 类 号：R284[医药卫生—中药学] R273[医药卫生—中医学]