Effect of Jianpi Shengxue Tablet on Iron Metabolism and Nutritional Status in Patients with Renal Anemia:A Prospective,Randomized,Open,Parallel Controlled and Multicenter Clinical Study  

作　　者：Juan YANG Meng-yuan LIANG Yu LI Hao ZHANG Wei LI Jing LV Li-ping DONG Jing-song JIN Cheng YANG Qing-hong ZHANG Li LONG Rong ZOU Yi GAO Dan SONG Chun-qin PAN Ying YAO Xiao-lin ZHAN Xiao-hui WANG 

机构地区：[1]Department of Nephrology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,430030,China [2]Department of Nephrology,The First People’s Hospital of Guiyang,Guiyang,550000,China [3]Department of Nephrology,The Third Xiangya Hospital,Central South University,Changsha,410000,China [4]Department of Nephrology,The First Affiliated Hospital of Xi’an Jiaotong University,Xi’an,710061,China [5]Department of Nephrology,Wuhan No. 4 Hospital,Wuhan,430033,China [6]Department of Nephrology,Hubei Provincial Hospital of Traditional Chinese Medicine,Wuhan,430060,China [7]Department of Nephrology,Central Theater General Hospital of PLA,Wuhan,430064,China [8]Department of Nephrology,Taihe Hospital,Shiyan,442000,China [9]Department of Nephrology,Third People’s Hospital of Hubei Province,Wuhan,430033,China [10]Department of Nephrology,Hubei Province Integrated Traditional Chinese and Western Medicine Hospital of Hubei province,Wuhan,430024,China [11]Department of Nephrology,Xi’an No.3 Hospital,Affiliated Hospital of Northwest University,Xi’an,710000,China [12]Department of Nephrology,Shenzhen Guangming District People’s Hospital,Shenzhen,518000,China [13]Department of Nephrology,Xiantao First People’s Hospital,Xiantao,433000,China [14]Department of Nutrition,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,430030,China [15]Department of Nephrology,Huangshi Central Hospital,Huangshi,435000,China [16]Department of Nephrology,The Fifth Hospital of Wuhan,Wuhan,430050,China

出　　处：《Current Medical Science》2024年第3期603-610,共8页当代医学科学（英文）

基　　金：financially supported by the National Natural Science Foundation of China(No.82170701).

摘　　要：Objective This study aimed to analyze the clinical efficacy of the Jianpi Shengxue tablet for treating renal anemia.Methods A total of 200 patients with renal anemia from December 2020 to December 2022 were enrolled and randomly divided into two groups.Patients in the control group were treated with polysaccharide-iron complex,and those in the experimental group were administered Jianpi Shengxue tablet.After 8 weeks of continuous treatment,the therapeutic outcomes regarding anemia were compared between the two groups.Results After treatment,the red blood cell(RBC)count,hematocrit(HCT),reticulocyte percentage(RET),ferritin(SF),serum iron(SI),transferrin saturation(TSAT),and serum albumin(ALB)all increased(P<0.01),and the clinical symptom score and total iron binding capacity decreased(P<0.01)in the experimental group.Moreover,the improvements in RBC,HCT,RET,SF,SI,TAST,ALB,and clinical symptoms(fatigue,anorexia,dull skin complexion,numbness of hands and feet)in the experimental group were significantly greater than those in the control group(P<0.05).The total effective rate for treating renal anemia was significantly higher in the experimental group than in the control group(P<0.01).Conclusion The Jianpi Shengxue tablet demonstrates efficacy in treating renal anemia,leading to significant improvements in the laboratory examination results and clinical symptoms of patients with renal anemia.

关 键 词：Jianpi Shengxue tablet renal anemia RANDOMIZED OPEN parallel control multicenter clinical study 

分 类 号：R692[医药卫生—泌尿科学]