甲状腺结节患者术后康复期间分别服用甲状腺片和左甲状腺素钠片的效果对比  

Comparison of the Effects of Taking Thyroid Tablets and Levothyroxine Sodium Tablets During Postoperative Rehabilitation of Patients with Thyroid Nodules

作　　者：赵宗彦 李峰 ZHAO Zongyan;LI Feng(Department of Surgery,Second People’s Hospital of Puyang County,Puyang 457100,Henan,China)

机构地区：[1]濮阳县第二人民医院外科,河南濮阳457100

出　　处：《中国药物滥用防治杂志》2024年第5期860-863,共4页Chinese Journal of Drug Abuse Prevention and Treatment

摘　　要：目的:探讨左甲状腺素钠片辅助甲状腺腺叶切除术治疗甲状腺结节患者的效果。方法:选择2020年2月—2023年1月在本院接受治疗的甲状腺结节患者79例,随机分为联合组40例和对照组39例。所有患者都给予甲状腺腺叶切除术治疗,对照组给予甲状腺片治疗,联合组给予左甲状腺素钠片治疗,比较两组治疗效果、甲状腺结节最大直径、最大横截面积、不良反应发生率及甲状腺激素水平。结果:治疗3周后,联合组总有效率为97.50%,高于对照组的82.05%(P<0.05);联合组治疗3周后甲状腺结节最大直径与最大横截面积低于对照组(P<0.05);联合组良反应发生率与对照组比较,差异无统计学意义(P>0.05)。联合组血清FT3、FT4含量高于对照组(P<0.05)。结论:左甲状腺素钠片辅助甲状腺腺叶切除术治疗甲状腺结节能提高治疗效果,并不会增加不良反应发生率,还可降低甲状腺结节的最大直径与最大横截面积,促进血清FT3、FT4的分泌。Objective:To investigate the effect of levothyroxine sodium tablets assisted thyroid lobectomy in the treatment of patients with thyroid nodules.Methods:A total of 79 patients with thyroid nodules who were treated in the hospital from February 2020 to January 2023 were randomly divided into combined group(40 patients)and control group(39 patients).All patients were treated with thyroid lobectomy.The control group was treated with thyroid tablets,and the combined group was treated with levothyroxine sodium tablets.The therapeutic effects,maximum diameter of thyroid nodules,maximum cross-sectional area,incidence of adverse reactions and thyroid hormone levels were compared between the two groups.Results:After 3 weeks of treatment,the total effective rate of the combined group was 97.50%,which was higher than 82.05%of the control group(P<0.05);the maximum diameter and maximum cross-sectional area of thyroid nodules in the combined group were lower than those in the control group(P<0.05);there was no significant difference in the incidence of good reaction between the combined group and the control group(P>0.05);the levels of serum FT3 and FT4 in the combined group were higher than those in the control group(P<0.05).Conclusion:Levothyroxine sodium tablets assisted thyroid lobectomy in the treatment of thyroid nodules can improve the therapeutic effect and will not increase the incidence of adverse reactions.It can also reduce the maximum diameter and maximum cross-sectional area of thyroid nodules and promote the secretion of serum FT3 and FT4.

关 键 词：左甲状腺素钠片 甲状腺腺叶切除术 甲状腺结节 不良反应 FT3 FT4 

分 类 号：R653[医药卫生—外科学]