全自动生化分析仪室间质评数据在献血者ALT初筛检测中的应用  

Application of the Data of the Automatic Biochemical Analyzer in the Laboratory Quality Assessment in the Primary Screening of ALT in Blood Donors

作　　者：江妮娜 蒋佳 金一鸣[1] 陆荣[1] 董丽[1] 王凯[1] JIANG Ni-na;JIANG Jia;JIN Yi-ming;LU Rong;DONG Li;WANG Kai(Suzhou City Blood Center,Suzhou,Jiangsu,215006,China)

机构地区：[1]苏州市中心血站血液检测科,江苏苏州215006

出　　处：《中国血液流变学杂志》2024年第1期129-132,共4页Chinese Journal of Hemorheology

基　　金：苏州市医学重点学科项目(SZXK202118);苏州市卫生科技项目(GWZX202203)。

摘　　要：目的利用全自动生化分析仪室间质评数据评估献血前ALT初筛设备性能,探讨提升献血前ALT初筛设备使用率和检测质量的新方法。方法利用国家卫健委临检中心全国ALT室间质评数据验证、确认全自动生化分析仪的性能,设立靶机。将靶机检测的ALT阳性标本在初筛干式生化分析仪进行同步检测、数据比对。结果ALT室间质评数据分析有利于完善设备的性能验证;初筛干式生化分析仪易受到温度和环境影响检测稳定性,有时与靶机差异明显。结论利用室间质评数据确定靶机后进行设备比对的模式,使ALT初筛设备的校验时效性和检测准确性都得到了补充,能够提高血液筛查的准确度、减少血液浪费。Objective The performance of ALT preliminary screening equipment before blood donation was evaluated using the inter-room quality assessment data of automatic biochemical analyzer,and a new method to improve the utilization rate and detection quality of ALT preliminary screening equipment before blood donation was discussed.Methods A verify and confirmed performance of the automatic biochemical analyzer by using the national ALT room quality assessment data of the National Health and Health Commission's Clinical Inspection Center,and set up the target machine to conduct synchronous detection and data comparison on the ALT positive samples detected by the target machine in the primary screening dry biochemical analyzer.Results ALT inter-room quality assessment data analysis is conducive to improve the performance verification of equipment.The primary screening dry biochemical analyzer is easily affected by temperature and environment,and its detection stability is sometimes significantly different from the target machine.Conclusion The mode of equipment comparison after the target machine is determined by the inter-room quality assessment data,which complements the validation timeliness and detection accuracy of the ALT primary screening equipment,can improve the accuracy of blood screening and reduce blood waste.

关 键 词：室间质评 丙氨酸氨基转移酶 性能验证 生化分析仪 

分 类 号：R457.12[医药卫生—治疗学]