双心干预对急性心力衰竭患者下肢深静脉血栓形成及凝血功能的影响  

Effect of psychological and biological intervention on lower extremity deep venous thrombosis and blood coagulation function in patients with acute heart failure

作　　者：张燕 孙美艳 秦岚[1] Zhang Yan;Sun Meiyan;Qin Lan(Department of Emergency,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China;Department of Intervention,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China)

机构地区：[1]首都医科大学附属北京友谊医院急诊科,北京100050 [2]首都医科大学附属北京友谊医院介入科,北京100050

出　　处：《血管与腔内血管外科杂志》2024年第5期557-561,共5页Journal of Vascular and Endovascular Surgery

摘　　要：目的探讨双心干预对急性心力衰竭(AHF)患者下肢深静脉血栓(DVT)形成及凝血功能的影响。方法收集2020年4月至2023年4月首都医科大学附属北京友谊医院收治的168例AHF患者的临床资料,按住院期间是否进行双心干预分为干预组(n=81)和对照组(n=87)。比较两组患者的生物学治疗相关指标、下肢DVT发生率、凝血功能指标。结果干预组患者下肢DVT发生率为2.5%(2/81),低于对照组患者的10.3%(9/87),差异有统计学意义(P﹤0.05)。复查时,干预组患者D-二聚体水平低于对照组患者,两组患者凝血酶原时间、活化部分凝血活酶时间均较入院时延长,且干预组患者凝血酶原时间、活化部分凝血活酶时间均长于对照组患者,差异均有统计学意义(P﹤0.05)。两组患者住院期间均未发现明显的出血并发症。结论双心干预可以有效预防AHF患者急性期发生下肢DVT的风险,并具有较高的安全性,值得临床推广。Objective To investigate the effect of psychological and biological intervention on the formation of lower extremity deep vein thrombosis(DVT)and blood coagulation function in patients with acute heart failure(AHF).Method Clinical data of 168 patients with AHF admitted to Beijing Friendship Hospital,Capital Medical University from April 2020 to April 2023 were collected,they were divided into intervention group(n=81)and control group(n=87)according to whether they received bicardiac intervention during hospitalization.The biological treatment related indexes,lower extremity DVT incidence and coagulation function indexes were compared between the two groups.Result The incidence of extremity DVT in the intervention group was 2.5%(2/81),lower than that in the control group of 10.3%(9/87),the difference was statistically significant(P<0.05).At review,the D-dimer level of the intervention group was lower than that of the control group,the prothrombin time and activated partial thromboplastin time of the two groups were longer than those of the admission,the prothrombin time and activated partial thromboplastin time of the intervention group were longer than those of the control group,the differences were statistically significant(P<0.05).No significant bleeding complications were found in both groups during hospitalization.Conclusion Psychological and biological intervention can effectively reduce the risk of lower extremity DVT in acute phase of AHF patients,and has high safety,which is worthy of clinical promotion.

关 键 词：急性心力衰竭 深静脉血栓 双心干预 

分 类 号：R543[医药卫生—心血管疾病]