阿奇霉素联合特布他林雾化吸入治疗肺炎支原体肺炎患儿的临床疗效研究  

Clinical Effi cacy of Azithromycin Combined with Terbutaline Nebulized Inhalation in the Treatment of Children with Mycoplasma Pneumoniae Pneumonia

作　　者：梁正[1] Liang Zheng(The First People’s Hospital of Nanning,Nanning,Guangxi 530022)

机构地区：[1]南宁市第一人民医院,广西南宁530022

出　　处：《科技与健康》2024年第11期49-52,共4页Technology and Health

摘　　要：分析阿奇霉素联合特布他林雾化吸入在肺炎支原体肺炎患儿治疗中的应用效果.选取2020年6月-2023年7月南宁市第一人民医院儿科收治的50例肺炎支原体肺炎患儿为研究对象,随机将患儿分为对照组和观察组两组,每组各25例,对照组实施阿奇霉素治疗,观察组在对照组治疗基础上联合特布他林雾化吸入治疗.比较两组患儿治疗效果.结果显示,观察组患儿临床治疗总有效率高于对照组(P<0.05);治疗后,观察组TNF-α、IL-17、PCT指标水平均低于对照组(P<0.05);治疗后,观察组患儿咳嗽症状积分低于对照组(P<0.05);观察组各项临床症状消失时间均短于对照组(P<0.05);治疗后,观察组患儿CD3^(+)、CD4^(+)、CD8^(+)、CD4^(+)/CD8^(+)水平均高于对照组(P<0.05).研究发现,阿奇霉素与特布他林雾化吸入联合治疗肺炎支原体肺炎患儿效果显著,可减轻患儿炎症反应,降低咳嗽评分,缩短临床症状消失时间,改善细胞免疫功能,且不会增加不良反应,值得推广应用.Analyze the application effect of azithromycin combined with terbutaline nebulized inhalation in the treatment of children with Mycoplasma pneumoniae pneumonia.Fifty children with Mycoplasma pneumoniae pneumonia admitted to the Pediatric Department of The First People’s Hospital of Nanning from June 2020 to July 2023 were selected as the study subjects.The children were randomly divided into a control group and an observation group,with 25 cases in each group.The control group received treatment with azithromycin,while the observation group received treatment with nebulized terbutaline inhalation in addition to the control group.Compare the treatment effects of two groups of pediatric patients.The results showed that the total effective rate of clinical treatment in the observation group was higher than that in the control group(P<0.05);After treatment,the levels of TNF-α,IL-17,and PCT indicators in the observation group were lower than those in the control group(P<0.05);After treatment,the cough symptom score of the observation group was lower than that of the control group(P<0.05);The disappearance time of various clinical symptoms in the observation group was shorter than that in the control group(P<0.05);After treatment,the levels of CD3^(+),CD4^(+),CD8^(+),CD4^(+)/CD8^(+)in the observation group were higher than those in the control group(P<0.05).Research has found that the combination of azithromycin and terbutaline nebulized inhalation has a significant effect on the treatment of children with Mycoplasma pneumoniae pneumonia.It can alleviate inflammation,lower cough scores,shorten the time for clinical symptom disappearance,improve cellular immune function,and do not increase adverse reactions.It is worth promoting and applying.

关 键 词：特布他林 雾化吸入 肺炎支原体肺炎 小儿 炎症指标 

分 类 号：R725.6[医药卫生—儿科]