肺气肿对阻塞性睡眠呼吸暂停综合征患者睡眠呼吸监测指标的影响  

Analysis of the Effects of Emphysema on Monitoring Indexes of Sleep Breathing and Pulmonary Function in Patients with Obstructive Sleep Apnea Syndrome

作　　者：廖秀枝 吴凯钦 陈清妹 LIAO Xiuzhi;WU Kaiqin;CHEN Qingmei(Sanming First Hospital Fujian,Sanming 365000,China;Sanming Integrated Traditional Chinese and Western Medicine Hospital,Sanming 365000,China)

机构地区：[1]三明市第一医院,三明365000 [2]三明市中西医结合医院,三明365000

出　　处：《世界睡眠医学杂志》2024年第5期1181-1183,共3页World Journal of Sleep Medicine

摘　　要：目的:探讨合并肺气肿对阻塞性睡眠呼吸暂停综合征(OSAS)患者睡眠呼吸监测指标的影响。方法:选取2022年4月至2023年9月三明市第一医院收治的OSAS患者72例作为研究对象,按照是否合并肺气肿分为对照组和观察组,对照组为单纯OSAS患者不合并肺气肿(n=41),观察组合并肺气肿(n=31),采用多导睡眠呼吸监测器监测2组患者的睡眠呼吸情况,并比较睡眠呼吸监测指标,比较2组患者的肺功能指标水平,比较2组患者睡眠状态下的血氧相关指标,比较2组患者睡眠质量。结果:观察组患者的睡眠监测指标均显著高于对照组,差异有统计学意义(P<0.05),观察组患者的FEV_(1)%、FEV_(1)/FVC以及TV均显著低于对照组,差异有统计学意义(P<0.05),观察组患者的血氧饱和度均显著高于对照组,差异有统计学意义(P<0.05),观察组最低80%以下氧饱和度次数和最低80%以下氧饱和度时间均显著低于对照组,差异有统计学意义(P<0.05),观察组患者的PSQI评分显著低于对照组,差异有统计学意义(P<0.05)。结论:合并肺气肿对OSAS患者的睡眠呼吸监测指标、肺功能指标以及血氧含量均会产生不良影响,临床上可针对合并疾病的患者及时作出治疗方案。Objective:To investigate the effects of Obstructive Sleep Apnea Syndrome(OSAS)combined with emphysema on the monitoring indexes of sleep respiration and pulmonary function.Methods:The clinical data of 31 patients with OSAS combined with emphysema treated in a hospital from April 2022 to September 2023 were retrospectively analyzed,and they were used as the observation group,and 41 patients with OSAS alone were included as the control group during the same period.Polysomnographic respiratory monitor was used to monitor the sleep breathing of patients in the 2 groups,and the monitoring indexes of sleep breathing,lung function indexes of patients in the 2 groups,blood oxygen related indexes in the sleep state of patients in the 2 groups,and sleep quality of patients in the 2 groups were compared.Results:Sleep monitoring index in the observation group were significantly higher than those in the control group(P<0.05),the differences were statistically significant;FEV_(1)%,FEV_(1)/FVC and TV of patients in the observation group were significantly lower than those in the control group(P<0.05),the differences were statistically significant.The minimum oxygen saturation and average oxygen saturation of patients in the observation group were significantly higher than those in the control group(P<0.05),and the difference was statistically significant.The number of oxygen saturation below 80%and the time of oxygen saturation below 80%in the observation group were significantly lower than those in the control group(P<0.05),and the difference was statistically significant.The PSQI score of the observation group was significantly lower than that of the control group,with statistical significance(P<0.05).Conclusion:Combined emphysema has adverse effects on sleep respiratory monitoring index,pulmonary function index and blood oxygen content in OSAS patients.Clinical treatment can be made in time for patients with combined disease.

关 键 词：肺气肿 阻塞性睡眠呼吸暂停综合征 睡眠呼吸监测 肺功能 血氧指标 睡眠呼吸暂停低通气指数 血氧饱和度 入睡潜伏期 

分 类 号：R338.63[医药卫生—人体生理学]