环形电刀切除术对子宫颈高级别鳞状上皮内病变患者分娩的影响  

Effect of loop electrosurgical excision procedure on delivery in patients with high-grade squamous intraepithelial lesions of the cervix

作　　者：满玮平 石衍颖 张子慧[1] MAN Weiping;SHI Yanying;ZHANG Zihui(Department of Gynecology,Pingdu People's Hospital,Qingdao,Shandong,266700,China)

机构地区：[1]平度市人民医院妇科,山东青岛266700

出　　处：《当代医学》2024年第8期77-80,共4页Contemporary Medicine

摘　　要：目的探讨环形电刀切除术(LEEP)对子宫颈高级别鳞状上皮内病变(HSIL)患者分娩的影响。方法选取2020年1月至2022年6月平度市人民医院收治的80例HSIL患者作为研究对象,按照随机数字表法分为对照组与观察组,每组40例。对照组采用冷刀锥切术(CKC)治疗,观察组采用环形电刀切除术(LEEP)治疗,比较两组围手术期指标、临床疗效、分娩情况、围产儿不良结局及术后并发症发生情况。结果两组锥切组织面积比较差异无统计学意义;观察组手术时间、切口愈合时间及住院时间均短于对照组,术中出血量少于对照组,差异有统计学意义(P<0.05)。两组治愈率、复发率比较差异无统计学意义。两组妊娠率、流产率、早产率、阴道分娩率及剖宫产率比较差异无统计学意义。观察组围生儿不良结局发生率15.63%,低于对照组的42.86%,差异有统计学意义(P<0.05)。观察组术后并发症发生率为7.50%,低于对照组的20.00%,差异有统计学意义(P<0.05)。结论LEEP和CKC两种术式治疗HSIL患者疗效相当,相对于CKC,LEEP术式具有操作方便、无需麻醉、术中出血量少、手术时间短、术后恢复快及对妊娠结局影响小等优点,值得临床推广应用。Objective To explore the effect of loop electrosurgical excision procedure(LEEP)on delivery in patients with high-grade squamous intraepithelial lesions(HSIL)of the cervix.Methods 80 HSIL patients admitted to Pingdu People's Hospital from January 2020 to June 2022 were selected as the study subjects,they were randomly divided into the control group and the observation group by the random number table method,with 40 cases in each group.The control group was treated with cold knife conization(CKC),and the observation group was treated with loop elec-trosurgical excision procedure(LEEP),the perioperative indicators,clinical efficacy,delivery status,adverse perinatal outcomes and postoperative complications were compared between the two groups.Results There was no significant difference in the area of conization tissue between the two groups;the operation time,incision healing time and hospitalization time in the observation group were all shorter than those in the control group,and the intraoperative blood loss was less than that in the control group,the differences were statistically significant(P<0.05).There was no signifi-cant difference in the cure rate and recurrence rate between the two groups.There was no significant difference in pregnancy rate,abortion rate,pre-mature delivery rate,vaginal delivery rate and cesarean section rate between the two groups.The incidence of adverse perinatal outcomes in the ob-servation group was 15.63%,which was lower than 42.86%in the control group,the difference was statistically significant(P<0.05).The incidence of postoperative complications in the observation group was 7.50%,which was lower than 20.00%in the control group,and the difference was statis-tically significant(P<0.05).Conclusion The efficacy of LEEP and CKC in the treatment of HSIL patients is similar.Compared with CKC,LEEP has the advantages of convenient operation,no anesthesia,less intraoperative blood loss,shorter operation time,faster postoperative recovery and less impact on pregnancy outcome,and is worthy

关 键 词：子宫颈高级别鳞状上皮内病变 环形电刀切除术 分娩情况 妊娠结局 

分 类 号：R719[医药卫生—妇产科学]