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作 者:梁维 杨克波 蒋立丹 王爱民 LIANG Wei;YANG Kebo;JIANG Lidan;WANG Aimin(Dazu District Center for Disease Control and Prevention,Chongqing 402360,China)
机构地区:[1]重庆市大足区疾病预防控制中心,重庆402360
出 处:《上海预防医学》2024年第6期563-565,共3页Shanghai Journal of Preventive Medicine
摘 要:【目的】了解2023年重庆市大足区致倦库蚊成蚊和家蝇成蝇对常见杀虫剂的抗药性情况,为合理使用卫生杀虫剂提供科学依据。【方法】分别采用成蚊接触筒法和成蝇点滴法进行抗药性测定。【结果】2023年重庆市大足区致倦库蚊成蚊对0.25%氯菊酯、0.025%高效氯氰菊酯、0.025%溴氰菊酯、5%马拉硫磷、0.1%残杀威24 h死亡率分别为37.35%、21.92%、28.33%、96.43%、95.38%。家蝇成蝇对95.8%高效氯氰菊酯、97%毒死蜱、90%溴氰菊酯、95%敌敌畏4种杀虫剂测定的半数致死剂量(LD_(50))值分别为雌性2.572、0.329、0.406、0.492μg,抗性倍数分别为829.68、7.65、53.42、46.42。【结论】大足区致倦库蚊成蚊及家蝇成蝇对常用杀虫剂均产生了不同程度的抗药性,因此对已产生较高抗药性的杀虫剂应暂停使用,对可能抗性和低抗水平的杀虫剂可采取药物混配、轮换施药等方式使用。同时应继续做好抗药性变化情况的监测,指导杀虫剂的合理使用。[Objective]To determine the resistance of adult Culex quinquefasciatus and Musca domestica to commonly used insecticides in Dazhu District of Chongqing in 2023,and provide scientific evidence for rational use of hygienic insecticides.[Methods]Drug resistance was determined by using adult mosquito contact tube method and adult fly drop method.[Results]In 2023,the 24-hour mortality rate of adult Culex quinquefasciatus in Dazu District,Chongqing,against permethrin(0.25%),beta-cypermethrin(0.025%),deltamethrin(0.025%),malathion(5%)and propoxur(0.1%)was 37.35%,21.92%,28.33%,96.43%,and 95.38%,respectively.The median lethal dose(LD_(50))value of female adult Musca domestica against beta-cypermethrin(95.8%),chlorpyrifos(97%),deltamethrin(90%)and dichlorvos(95%)was 2.572µg,0.329µg,0.406µg,and 0.492µg,respectively,with resistance of 829.68,7.65,53.42,and 46.42 folds to the above tested insecticides.[Conclusion]Adult Culex quinquefasciatus and Musca domestica in Dazu District show various degrees of resistance to commonly used insecticides.It warrants suspending the insecticides with high resistance,whereas mixedly and alternatively administering the insecticides with possible resistance and low resistance.Additionally,we should continue to monitor the resistance and guide the rational use of insecticides。
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