281例新型冠状病毒感染女性月经状况及影响因素分析  

Analysis of menstrual conditions and influencing factors in 281 women infected with COVID-19

作　　者：杨蕊 陈旦平 章晓洁 唐文婕 夏馨 陈颖娟 薛佳颖 许江虹 YANG Rui;CHEN Danping;ZHANG Xiaojie;TANG Wenjie;XIA Xin;CHEN Yingjuan;XUE Jiaying;XU Jianghong(Department of TCM Gynecology,Jing'an District Hospital of Traditional Chinese Medicine,Shanghai)

机构地区：[1]上海市静安区中医医院妇科,上海200072

出　　处：《上海预防医学》2024年第6期582-588,共7页Shanghai Journal of Preventive Medicine

基　　金：上海市静安区卫生健康委员会中医药临床重点专科建设项目(JA2020-Z006);上海市静安区卫生健康委员会中医专病诊疗中心建设项目(JA2021-ZLZX001);上海市静安区卫生健康委员会2023年医学科研课题中医专项(2023ZY03)。

摘　　要：【目的】调查上海市新型冠状病毒(简称“新冠”)感染女性的月经状况并分析其影响因素。【方法】采用问卷调查方式收集2022年12月—2023年3月上海市新冠感染女性的月经资料281例,内容包括平时月经状况、感染新冠后最近一次月经状况、感染症状、使用药物等。根据受访者经期与感染期交叉时相将样本分成感染期与经期存在重合组(阳性组)和转阴后月经来潮组(转阴组)进行对比分析。【结果】281例受访者中196例(65.8%)月经发生改变。其中145例(51.6%)出现月经量、色、质的改变,109例(38.8%)出现经期或周期改变。两组均出现经量减少(22.1%)、颜色变深(23.49%)、质地变稠(21.0%)、血块变多(16.7%)、经期延长(21.8%)。阳性组月经量色质变化率(56.8%,69/110)高于转阴组(37.3%,76/171)(P<0.05)。在月经周期变化方面,阳性组月经提前率(14.5%)高于转阴组(3.5%)(P<0.05),转阴组月经延后率(25.1%)高于阳性组(5.5%)(P<0.05)。相关性分析显示,咽痛和月经改变存在弱相关(r=0.154,P<0.05)。【结论】感染新冠的部分女性短期内月经状况发生改变,出现量减少、色深、质稠、血块多、经期延长,反映血瘀病机;月经来潮发生在感染期以月经提前为主,在转阴后以月经延后为主。[Objective]To investigate the menstrual conditions of women infected with COVID-19 in Shanghai and analyze the influencing factors.[Methods]From December 2022 to March 2023,menstrual data from 281 women infected with COVID-19 in Shanghai were collected with a questionnaire survey,including usual menstrual characteristics,the most recent menstrual period post-infection,symptoms of infection,and medication usage.According to the crossover period between the menstrual period and the infection period of the respondents,the samples were divided into two groups for comparative analysis:those whose menstrual and infection periods overlapped(positive group)and those whose menstruation started after conversion to virus-negative(negative conversion group).[Results]Among the 281 respondents,196(65.8%)experienced menstrual changes.Among them,145(51.6%)had changes in menstrual volume,color and texture,and 109(38.8%)had changes in menstrual duration or cycle.Decreased menstrual volume(22.1%),darker color(23.49%),thicker texture(21.0%),increased blood clots(16.7%),and prolonged duration(21.8%)were observed in both groups.The rate of changes in menstrual volume,color,and texture was higher in the positive group(56.8%,69/110)than that in negative group(37.3%,76/171)(P<0.05).Regarding the menstrual cycle changes,the rate of early onset was higher in the positive group(14.5%)compared to the negative conversion group(3.5%)(P<0.05),while the rate of delayed menstruation was higher in the negative conversion group(25.1%)than that in the positive group(5.5%)(P<0.05).Correlation analysis showed a weak association between sore throat and menstrual changes(r=0.154,P<0.05).[Conclusion]Some women infected with COVID-19 experience short-term changes in their menstrual conditions,characterized by reduced volume,darker color,thick texture,increased clots,and prolonged menstrual duration,reflecting a pathogenesis of blood stasis.Menstruation during the infection period tends to occur earlier,while delayed menstruation is more prevalent at post-

关 键 词：新型冠状病毒感染 月经 影响因素 血瘀 中医 

分 类 号：R17[医药卫生—妇幼卫生保健]