富铁大米对缺铁性贫血大鼠的改善作用  

Ameliorating Effect of Iron-Rich Rice on Rats with Iron Deficiency Anemia

作　　者：付清 王赵劼 徐婷 柯建杨 宫智勇 方敏 FU Qing;WANG Zhaojie;XU Ting;KE Jianyang;GONG Zhiyong;FANG Min(Key Laboratory of Agricultural Products Processing and Transformation of Hubei Province,Food Safety Research Center,Key Research Institute of Humanities and Social Sciences of Hubei Province,College of Food Science and Engineering,Wuhan Polytechnic University,Wuhan 430023,China)

机构地区：[1]武汉轻工大学食品科学与工程学院,湖北省农产品加工与转化重点实验室,湖北省高校人文社会科学重点研究基地食品安全研究中心,湖北武汉430023

出　　处：《食品科技》2024年第5期147-153,共7页Food Science and Technology

基　　金：横向课题(101-08023031)。

摘　　要：目的:缺铁性贫血(Iron deficiency anemia,IDA)是较严重的营养问题之一。一般大米每千克含铁量不超过2.0 mg。研究选取的某品牌大米,含铁量为5.33 mg/kg,高于普通大米铁含量2~3倍。将该富铁大米掺入饲料中,制备55%富铁大米饲料(富铁大米替代正常饲料中的淀粉)。评估该富铁大米对IDA大鼠的影响效果。方法:采用给予低铁饲料结合定期少量剪尾放血的方法建立IDA大鼠模型。选取正常饲料喂养的同龄健康大鼠作为空白对照组;将IDA大鼠随机分为正常饲料组、阳性对照组、低铁饲料组、富铁大米饲料组。实验结束时观察动物的生长体态情况,再分别测定各组动物的脏器指数、血红蛋白、血清铁、肝脏和脾脏的铁含量。结果:与正常饲料组相比,富铁大米饲料组大鼠体质量有所升高,心脏、脾脏指数均显著降低(P<0.05),血红蛋白水平显著升高(P<0.05)。此外,富铁大米饲料组的血清铁、肝、脾中铁含量较正常饲料组显著升高(P<0.05)。结论:该富铁大米对IDA大鼠的贫血有改善作用。Objective:Iron deficiency anemia (IDA) is one of the more serious nutritional problems.Generally,the iron content of rice does not exceed 2.0 mg per kilogram.The iron content of a certain brand of rice selected in the study was 5.33 mg/kg,which was 2–3 times higher than ordinary rice.The iron-rich rice was mixed into the feed to prepare 55% iron-rich rice feed (iron-rich rice replaces the starch in the normal feed).To evaluate the effect of the iron-rich rice on IDA rats.Methods:An IDA rat model was established by giving low-iron diet combined with regular tail clipping and bloodletting.Healthy rats of the same age fed with normal diet were selected as the blank control group,and IDA rats were randomly divided into normal diet group,positive control group,low-iron diet group and iron-rich rice diet group.At the end of the experiment,the growth and posture of the animals were observed,and the organ index,hemoglobin (Hb),serum iron (SI),liver and spleen iron contents of each group of animals were measured.Results:Compared with the normal diet group,the body weight of the iron-rich rice diet group was significantly increased,heart and spleen indices were significantly decreased (P<0.05),and the level of Hb was significantly increased (P<0.05).In addition,the iron content in SI,liver and spleen of the iron-rich rice diet group was significantly higher than that of the normal diet group (P<0.05).Conclusion:The iron-rich rice can improve the anemia of IDA rats.

关 键 词：富铁大米 缺铁性贫血 血红蛋白 血清铁 

分 类 号：TS218[轻工技术与工程—粮食、油脂及植物蛋白工程]