出 处:《中国药物与临床》2024年第12期769-773,共5页Chinese Remedies & Clinics
基 金:浙江省医药卫生科技计划项目(2020PY076)。
摘 要:目的探讨新型面罩下七氟烷吸入全身麻醉应用于患儿的麻醉有效性和安全性。方法选取2020年1月至2022年12月在嘉兴市中医医院接受手术治疗的眼疾患儿92例,按麻醉方法分为观察组和对照组。观察组经新型面罩吸入诱导麻醉后置入喉罩,对照组经普通面罩吸入诱导麻醉后置入喉罩,2组均机械通气全身麻醉,探讨2组麻醉有效性和安全性。结果①血流动力学指标及呼吸情况:观察组及对照组各时刻血流动力学指标[心率、平均动脉压(MAP)]比较,差异均无统计学意义(P>0.05);且2组间比较,各时刻血流动力学指标(心率、MAP)亦差异无统计学意义(P>0.05);2组各时刻呼吸情况[血氧饱和度(SpO_(2))、呼气末二氧化碳分压(PETCO_(2))、吸气峰压(PIP)]比较,差异均无统计学意义(P>0.05)。②置入情况:观察组一次置入成功率明显高于对照组(P<0.05)。③术毕恢复情况:2组自主呼吸恢复时间及苏醒时间对比差异无统计学意义(P>0.05);但观察组定向力恢复时间以及改良Aldrete评分达到9分的时间相较于对照组明显缩短,组间差异有统计学意义(P<0.05)。④麻醉不良反应发生率:较于对照组(20%),观察组(9%)不良反应发生率降低(P<0.05)。结论新型吸入麻醉面罩下七氟烷吸入全身麻醉在患儿眼科麻醉手术中具有较好的使用效果,麻醉诱导后喉罩的一次成功置入率较高,且麻醉不良反应发生率降低,是一种兼具有效性及安全性的麻醉呼吸工具。Objective To investigate the efficacy and safety of sevoflurane inhalation anesthesia under a new type of inhalation anesthesia mask to improve anesthesia in patients undergoing general anesthesia with spon-taneous ventilation.Methods A total of 92 children with strabismus who underwent surgical treatment in the Jiaxing Hospital of Traditional Chinese Medicine from January 2020 to March 2022 were divided into an obser-vation group and a control group by treatment.The observation group was anesthetized with a new type of mask inhalation and placed with a laryngeal mask,while the control group was anesthetized with a regular mask inhalation and placed with a laryngeal mask.Both groups received mechanical ventilation and general anesthesia to explore the effec-tiveness and safety of anesthesia.Results①Hemodynamic indexes and respiratory conditions:there was no significant difference in hemodynamic indicators(HR,MAP)between the observation group and the control group at each time point(P>0.05);Moreover,there was no significant difference in hemodynamic indicators(HR、MAP)between the two groups at each time point(P>0.05);There was no significant difference in respiratory status(SpO_(2),PETCO_(2) and PIP)between the two groups at different time(P>0.05).②Placement:the induction time was short in both groups,and the laryngeal mask was successfully inserted.Between them,the observation group had a signifi-cantly higher success rate of one-time insertion than the control group(P<0.05).③Recovery after operation:Two groups of spontaneous breathing recovery time and waking time comparison were no significant difference(P>0.05);However,the time of orientation recovery and the time of modified Aldrete score reaching 9 points in the observation group were significantly shorter than those in the control group,and the difference between the two groups was significant(P<0.05).④The incidence of adverse re-actions to anes-thesia:the incidence of adverse re-actions was 9%in the observation group and 20%in the control group.Co
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...