药剂师参与处方管理对门诊抗菌药物合理运用的影响研究  

Study on the influence of pharmacists'participation in prescription management on the rational use of antibacterial drugs in outpatient clinics

作　　者：尹训帅 YIN Xun-shuai(Department of Pharmacy,Sishui County People's Hospital,Jining 273200,China)

机构地区：[1]泗水县人民医院药剂科,273200

出　　处：《中国现代药物应用》2024年第13期137-140,共4页Chinese Journal of Modern Drug Application

摘　　要：目的探讨药剂师参与处方管理对门诊抗菌药物合理运用的影响。方法选择门诊接受抗菌药物治疗的患者100例,按照随机数字表方式分组,对照组50例采用常规处方管理,研究组50例则采用药剂师参与处方管理。对比两组抗菌药物的使用原因、联用情况、不合理使用情况、不良反应以及用药满意度。结果研究组治疗性用药率为74.00%,较对照组的40.00%高;而预防性用药率、无指征用药率分别为24.00%、2.00%,均较对照组的46.00%、14.00%低(P<0.05);研究组抗菌药物单一用药率62.00%高于对照组的42.00%,而三联及以上用药率10.00%则低于对照组的28.00%(P<0.05);研究组抗菌药物不合理使用率10.00%低于对照组的32.00%(P<0.05)。研究组抗菌药物使用后的不良反应率为8.00%,显著较对照组的22.00%低(P<0.05)。研究组用药满意度98.00%高于对照组的82.00%(P<0.05)。结论药剂师参与处方管理能明显提高门诊抗菌药物的应用合理性,并降低不良反应,从而提升患者用药满意度,值得推广。Objective To explore the influence of pharmacists'participation in prescription management on the rational use of antibacterial drugs in outpatient clinics.Methods 100 patients receiving antimicrobial drug therapy in outpatient clinics were selected and grouped according to a random number table;50 patients in the control group received routine prescription management,and 50 patients in the study group received prescription management involving pharmacists.The reasons for antimicrobial drug use,combination,irrational use,adverse reactions and medication satisfaction were compared between the two groups.Results The therapeutic medication rate in the study group was 74.00%,which was higher than 40.00% in the control group;the preventive and unindicated medication rates were 24.00% and 2.00%,both of which were lower than 46.00% and 14.00% in the control group(P<0.05).The single antimicrobial rate in the study group was 62.00%,which was higher than 42.00% in the control group,while the medication rate of triple and above was 10.00%,which was lower than 28.00% in the control group(P<0.05).The total incidence of unreasonable antimicrobial use in the study group was 10.00%,which was lower than 32.00%in the control group(P<0.05).The incidence of adverse reactions after antimicrobial use in the study group was 8.00%,which was significantly lower than 22.00% in the control group(P<0.05).The medication satisfaction rate of the patients in the study group was 98.00%,which was higher than 82.00% in the control group(P<0.05).Conclusion Pharmacists'participation in prescription management can significantly improve the rationality of antibiotics in outpatient clinics,and reduce adverse reactions,so as to improve medication satisfaction of patients,which is worth promoting.

关 键 词：药剂师 处方管理 门诊 抗菌药物 合理运用 不良反应 

分 类 号：R95[医药卫生—药学]