麦角新碱注射液联合缩宫素预防子宫收缩乏力性产后出血的效果  

Effect of ergometrine injection combined with oxytocin on preventing postpartum hemorrhage caused by uterine contraction fatigue

作　　者：李继强 Li Jiqiang(Department of Obstetrics,Xuzhou Jiulong Maternity Hospital,Xuzhou 221000,China)

机构地区：[1]徐州九龙妇产医院产科,江苏徐州221000

出　　处：《实用妇科内分泌电子杂志》2024年第14期62-64,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的分析麦角新碱注射液联合缩宫素预防子宫收缩乏力性产后出血的效果。方法选择于本院行剖宫产的60例产妇,按照随机数字表法分为两组,各30例。分娩后,对照组产妇予以静滴缩宫素治疗,研究组产妇予以静脉使用缩宫素+麦角新碱治疗。比较两组疗效。结果研究组产后各时段出血量、宫底位置均低于对照组,持续宫缩时间、持续恶露时间分别为(13.87±4.29)d、(1.69±0.38)d,均短于对照组的(21.86±5.35)d、(3.52±0.53)d(P<0.05)。治疗后,研究组凝血酶原时间、活化部分凝血活酶时间均短于对照组,D-二聚体、纤维蛋白原水平均高于对照组(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论产妇分娩后予以注射麦角新碱、缩宫素可有效预防子宫收缩乏力性产后出血,促进子宫复旧,改善产妇凝血功能,安全性好。Objective To analyze the effect of ergometrine injection combined with oxytocin on preventing postpartum hemorrhage caused by uterine contraction fatigue.Methods 60 parturients who underwent cesarean section in our hospital were randomly divided into two groups,each with 30 cases,using a random number table method.After delivery,the control group of parturients were treated with intravenous oxytocin,while the study group of parturients were treated with intravenous oxytocin+ergometrine.Compare the therapeutic effects of two groups.Results The postpartum blood losses and fundus positions in the study group were lower than those in the control group,while the duration of uterine contraction and lochia duration were(13.87±4.29)d and(1.69±0.38)d,respectively,which were shorter than(21.86±5.35)d and(3.52±0.53)d in the control group(P<0.05).After treatment,the prothrombin time and activated partial thromboplastin time in the study group were shorter than those in the control group,and the D-dimer and fibrinogen levels were higher than those in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Injecting ergometrine and oxytocin to postpartum women after delivery can effectively prevent uterine atony induced postpartum hemorrhage,promote uterine involution,improve coagulation function,and have good safety.

关 键 词：麦角新碱 缩宫素 子宫收缩乏力 产后出血 

分 类 号：R714.461[医药卫生—妇产科学]