舒芬太尼联合艾司氯胺酮用于腹腔镜妇科手术术后镇痛的效果分析  

Analysis of the effect of sufentanil combined with ketamine on postoperative analgesia in laparoscopic gynecological surgery

作　　者：林嘉欣 徐娇 任从才 邓嘉丽 Lin Jiaxin;Xu Jiao;Ren Congcai;Deng Jiali(Department of Anesthesiology,The Eighth Affiliated Hospital of Sun Yat-sen University(Futian,Shenzhen),Shenzhen 518000)

机构地区：[1]中山大学附属第八医院(深圳福田)麻醉科,广东深圳518000

出　　处：《实用妇科内分泌电子杂志》2024年第15期65-67,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探究舒芬太尼联合艾司氯胺酮用于腹腔镜妇科手术术后镇痛的效果。方法选取在本院进行腹腔镜妇科手术治疗的60例患者为研究对象,将患者随机分为3组,每组20例。对照组使用舒芬太尼镇痛,观察1组使用舒芬太尼复合小剂量艾司氯胺酮镇痛,观察2组使用舒芬太尼复合双倍剂量艾司氯胺酮镇痛,比较并分析3组镇痛效果。结果T_(3)时,3组评分均升高,并于T_(3)时达到高峰。T_(3)、T_(4)、T_(5)时疼痛评分均高于T_(1)时,同时点观察1组、观察2组的评分均低于对照组(P<0.05)。T_(1)时观察2组的镇静效果评分高于观察1组(P<0.05)。T_(3)、T_(4)、T_(5)时观察1组、观察2组的镇静效果评分高于对照组(P<0.05)。3组患者术后恶心、呕吐、瘙痒和精神症状发生例数较少,观察2组头晕发生率高于对照组和观察1组(P<0.05)。结论与单纯采用舒芬太尼行术后镇痛相比,舒芬太尼联合艾司氯胺酮可为腹腔镜妇科手术患者提供满意术后镇痛效果,未有精神症状发生,较低剂量艾司氯胺酮不良反应发生情况更少,建议临床推广。Objective To investigate the effect of sufentanil combined with ketamine on postoperative analgesia in laparoscopic gynecological surgery.Methods 60 patients who underwent laparoscopic gynecological surgery in our hospital were selected as the research subjects.The patients were randomly divided into three groups,with 20 cases in each group.The control group used sufentanil for pain relief,while the observation group used sufentanil combined with low-dose ketamine for pain relief.The observation group used sufentanil combined with double dose ketamine for pain relief,and the observation group used sufentanil combined with double dose ketamine for pain relief.The analgesic effects of the three groups were compared and analyzed.Results At T_(3),the scores of all three groups increased and reached a peak at T_(3).The pain scores at T_(3),T_(4),and T_(5),were higher than those at T_(1),while the scores of observation group 1 and observation group 2 were lower than those of the control group(P<0.05).At T_(1),the sedative effect score of Group 2 was higher than that of Group 1(P<0.05).At T_(3),T_(4),and T_(5),the sedative effect scores of observation group 1 and observation group 2 were higher than those of the control group(P<0.05).The incidence of postoperative nausea,vomiting,itching,and psychological symptoms was relatively low in the three groups of patients.The incidence of dizziness in the observation group 2 was higher than that in the control group and observation group 1(P<0.05).Conclusion Compared with using only sufentanil for postoperative pain relief,the combination of sufentanil and ketamine can provide satisfactory postoperative pain relief for patients undergoing laparoscopic gynecological surgery,with no occurrence of mental symptoms and fewer adverse reactions at lower doses of ketamine.Clinical promotion is recommended.

关 键 词：舒芬太尼 艾司氯胺酮 术后镇痛 腹腔镜妇科手术 

分 类 号：R614[医药卫生—麻醉学]