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作 者:石蓓 冯媛媛 Shi Bei;Feng Yuanyuan(Pharmacy Department of Jiangdu People's Hospital,Yangzhou,Jiangsu 225200,China)
机构地区:[1]江苏省扬州市江都人民医院,江苏扬州225200
出 处:《首都食品与医药》2024年第13期90-92,共3页Capital Food Medicine
摘 要:目的分析2型糖尿病患者常用口服降血糖药物的合理用药情况。方法以扬州市江都人民医院2023年6月-2023年11月收治2型糖尿病患者500例作为此次研究对象,总结常用口服降血糖药物的种类及名称,归纳给药方案,分析不合理用药的具体情况,统计患者发生药物不良反应的概率。结果临床较为常用的口服降血糖药物类型包括:双胍类、磺脲类等,常用的降血糖药物名称包括:二甲双胍、格列美脲、达格列净、格列吡嗪控释片等,其中达格列净使用频率位列第一,二甲双胍位列第二。双药联用降糖药物的占比率高于单独用药及多药联用(P<0.05)。目前临床不合理用药的情况包括:药物剂量不合理、药物种类不合理、药物联用不合理。此次共计21例患者出现不合理用药情况,占比4.20%。共计25例患者用药后出现不良反应,发生率为5.00%。结论该院2型糖尿病患者常用的口服降血糖药物以双胍类、磺脲类为主,达格列净、二甲双胍均为常用降糖药物,且该院口服降血糖药物使用基本合理,比较常见的不合理用药情况为联合用药不当,应予以重视。Objective To analyze the rational use of commonly used oral hypoglycemic drugs in patients with type 2 diabetes.Methods Taking 500 patients with type 2 diabetes admitted to Yangzhou Jiangdu People's Hospital from June 2023 to November 2023 as the target objects of this time,we summarized the types and names of commonly used oral hypoglycemic drugs,summarized the drug administration plan,analyzed the specific situation of irrational drug use,and counted the probability of adverse drug reactions in patients.Results The commonly used types of oral hypoglycemic drugs in clinical practice include metformin,sulfonylurea,etc.Commonly used hypoglycemic drug names include metformin,glimepiride,dapagliflozin,glipizide controlled-release tablets,etc.Among them,dapagliflozin ranks first in frequency of use and metformin ranks second.The proportion of dual drug combination hypoglycemic drugs is higher than that of single drug and multi drug combination(P<0.05).The current situation of irrational drug use in clinical practice includes:unreasonable drug dosage,unreasonable drug types,and unreasonable drug combination.A total of 21 patients experienced irrational medication use,accounting for 4.20%.A total of 25 patients experienced adverse reactions after medication,with an incidence rate of 5.00%.Conclusion The commonly used oral hypoglycemic drugs for patients with type 2 diabetes in our hospital are mainly biguanides and sulfonylureas.Daggligin and metformin are commonly used hypoglycemic drugs,and the use of oral hypoglycemic drugs in our hospital is basically reasonable.The common unreasonable use of drugs is improper combined use,which should be paid attention to.
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