超声左心室自动功能成像评估胰岛素泵输注治疗2型糖尿病合并肺结核左心室功能  

Assessment of ultrasound AFI on left ventricle for the effect of insulin pump infusion in treating T2DM complicated with left ventricular function of pulmonary tuberculosis

作　　者：杨丽萍[1] 李小卉 张晶[2] 赵艳君[3] 杨爱琼[1] Yang Liping;Li Xiaohui;Zhang Jing;Zhao Yanjun;Yang Aiqiong(Section of Special Diagnosis of Cadre Health Center,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China;The Second Department of General Medicine of Cadre Health Center,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China;Daytime Surgical Treatment Ward,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China)

机构地区：[1]新疆医科大学第一附属医院干部保健中心特诊区,乌鲁木齐830054 [2]新疆医科大学第一附属医院干部保健中心综合内二科,乌鲁木齐830054 [3]新疆医科大学第一附属医院日间手术治疗病房,乌鲁木齐830054

出　　处：《中国医学装备》2024年第7期82-86,共5页China Medical Equipment

基　　金：新疆维吾尔自治区自然科学基金青年基金项目(2017D01C334)。

摘　　要：目的:探索超声左心室自动功能成像(AFI)评估胰岛素泵输注治疗2型糖尿病(T2DM)合并肺结核左心室功能的效果。方法:选取2020年12月至2022年10月新疆医科大学第一附属医院收治的108例T2DM合并肺结核老年患者纳入观察组,选取同期在本院接受体检的90名健康体检者纳入健康对照组。观察组接受胰岛素泵的输注治疗,并于治疗前后采用超声左心室AFI评估左心室功能参数;健康对照组检查左心室指标及血糖指标。对比两组的临床指标以及超声参数上的差异性。结果:观察组治疗后与治疗前比较收缩压与空腹血糖水平均较低;观察组治疗后与治疗前分别与健康对照组相比长轴方向的全球纵向应变(GLPS-LAX)、四腔心切面的全球纵向应变(GLPS-A4C)及平均全球纵向应变(GLPS-AVG)比较均有所降低;观察组治疗后与治疗前相比GLPS-LAX、GLPS-AVG较高,差异有统计学意义(t=2.846、4.926,P<0.05)。结论:T2DM合并肺结核患者在经过胰岛素泵注射治疗后,通过采用超声左心室AFI对患者的左心室功能进行评估时发现,其左心室功能获得有效改善,采用超声左心室AFI评估T2DM合并肺结核左心室功能具有重要的临床意义。Objective:To investigate and analyze the assessment of ultrasonic AFI on left ventricle for the effect of insulin pump infusion in treating type 2 diabetes mellitus(T2DM)complicated with left ventricular function of pulmonary tuberculosis(PTB).Methods:From December 2020 to October 2022,a total of 108 elderly patients with T2DM complicated with PTB,who were treated at the First Affiliated Hospital of Xinjiang Medical University,were selected as the observation group.At the same time,90 healthy individuals who underwent physical examinations at the same hospital were selected as the healthy control group.The patients of observation group received infusion therapy with insulin pump,and the ultrasonic automated function imaging(AFI)on left ventricle was adopted to assess the parameters of the function of left ventricle pre and post treatment.The indicators of left ventricle and blood glucose of healthy control group were examined.The differences of clinical indicators and ultrasonic parameters between two groups were compared.Results:Compared with the systolic blood pressure and fasting blood glucose levels pretreatment,these indicators post treatment were lower in observation group.Compared with the global longitudinal peak Strain in long axis(GLPS-LAX),global longitudinal peak strain in apical four-chamber view(GLPSA4C)and global longitudinal peak strain average(GLPS-AVG)post and pretreatment of healthy control group,they decreased in observation group.Compared with GLPS-LAX and GLPS-AVG pretreatment of observation group,they were higher post treatment in observation group,and the differences were significant(t=2.846,4.926,P<0.05),respectively.Conclusion:After patients with T2DM complicated with PTB are treated by insulin pump infusion,the assessment of ultrasonic AFI on the function of left ventricle finds that the function of left ventricle of patients is effectively improved.Dynamic detection of the above indicators has important clinical significance in assessing the curative efficacy of disease.

关 键 词：超声左心室自动功能成像(AFI) 胰岛素泵 2型糖尿病(T2DM) 肺结核 左心室功能 

分 类 号：R445.1[医药卫生—影像医学与核医学]