轻度胃肠炎伴良性惊厥相关基因研究进展  

Progress of genes related to benign convulsions with mild gastroenteritis

作　　者：高玮 苏学文 Gao Wei;Su Xuewen(Department of Pediatrics,People's Hospital of the Inner Mongolia Autonomous Region,Hohhot 010010,China)

机构地区：[1]内蒙古自治区人民医院儿科,呼和浩特010010

出　　处：《国际儿科学杂志》2024年第5期321-325,共5页International Journal of Pediatrics

基　　金：内蒙古自治区自然科学基金(2018MS08067)。

摘　　要：轻度胃肠炎伴良性惊厥(benign convulsions with mild gastroenteritis,CwG)发病率逐年增加。丛集性惊厥发作是CwG的发病特征之一,且抗癫痫药物难以控制。关于CwG的发病机制错综复杂,是目前研究的热点,相关研究认为遗传因素在其发展中具有重要地位。基因研究通过深入探究CwG的病理机制,明确各相关基因在CwG发展中的作用,为CwG后期可能出现的临床症状提供早筛查、早预防、早诊断、早治疗的理论依据,从而为靶向治疗提供线索。该文就CwG相关基因研究进展进行综述,以便深入了解其发病机制,有效控制惊厥反复发作及预防后期可能临床症状的出现。The incidence of benign convulsions with mild gastroenteritis(CwG)is increasing year by year.Cluster seizures are one of the characteristics of CwG and are difficult to control with antiepileptic drugs.The pathogenesis of CwG is complex and is a hot topic of current research.Relevant studies believe that genetic factors play an important role in its development.By exploring the pathological mechanism of CwG and clarifying the role of related genes in the development of CwG,gene research provides a theoretical basis for early screening,early prevention,early diagnosis,and early treatment of the possible clinical symptoms of CwG in the later stage,so as to provide clues for targeted therapy.This article reviews the research progress of CwG related genes,in order to understand its pathogenesis,effectively control recurrent seizures and prevent the appearance of possible clinical symptoms in the later stage.

关 键 词：胃肠炎 惊厥 基因 

分 类 号：R725.7[医药卫生—儿科]