高速波前整形系统的研究进展  

A Review on High-Speed Wavefront Shaping System

作　　者：罗嘉伟 伍代轩 梁家俊 沈乐成 Luo Jiawei;Wu Daixuan;Liang Jiajun;Shen Yuecheng(School of Electronics and Information Technology,Sun Yat-Sen University,Guangzhou 510006,Guangdong,China;School of Information and Optoelectronic Science and Engineering,South China Normal University,Guangzhou 510631,Guangdong,China;State Key Laboratory of Precision Spectroscopy,East China Normal University,Shanghai 200241,China)

机构地区：[1]中山大学电子与信息工程学院,广东广州510006 [2]华南师范大学信息光电子科技学院,广东广州510631 [3]华东师范大学精密光谱科学与技术国家重点实验室,上海200241

出　　处：《激光与光电子学进展》2024年第10期48-58,共11页Laser & Optoelectronics Progress

基　　金：国家自然科学基金(12004446,92150102)。

摘　　要：生物组织折射率在微观上的不均匀分布造成了光学散射,进而导致了光在组织深处聚焦能力的丧失。波前整形技术通过补偿不同散射通道间的相位延迟,能够实现散射光的重新聚焦。该技术的有效实施依赖于散射过程的确定性,一旦散射过程在调控完成前发生变化,预补偿的相位将无法抵消散射带来的影响,最终会造成焦点强度的下降甚至是完全消失。然而在实际应用中,散射过程通常处于一个不断变化的动态状态,例如在生物活体内,血液的流动、心跳,以及呼吸等动态生理活动均会引起散射过程的动态变化。因此,为了保障波前整形技术在生物活体中的应用开展,提升波前整形系统的调控速度显得尤为关键。针对该问题,本综述主要对高速波前整形的发展现状进行了回顾,概述了调控速度的未来优化方向,分析并展望了其在生命科学中的潜在应用和前景。Optical scattering induced by microscopic inhomogeneities in the refractive index poses a remarkable challenge to achieve optical focusing inside deep biological tissues.The wavefront shaping technique is emerging as a promising solution to this challenge because optical focusing is achieved through scattering media by compensating phase delays among different scattering paths.The effectiveness of this technique relies on the deterministic design of the scattering medium because even minor changes in scatterers can disrupt phase compensation,thereby resulting in degraded focus quality or complete loss of focus.However,practical applications often involve dynamic scattering processes.For example,physiological activities in living organisms,such as blood flow,heartbeat,and breathing,induce dynamic scattering processes.Consequently,enhancing the modulation speed of the wavefront shaping system is crucial to ensure successful operation in biomedical applications involving live tissues.To address this challenge,this review offers a comprehensive introduction to the state of high-speed wavefront shaping systems,outlines future directions for optimizing system speed,analyzes potential applications in biomedical science,and provides a prospective outlook on the future development of wavefront shaping.

关 键 词：波前整形 高速调控 散射介质 光学相位共轭 引导星 超声调制 

分 类 号：O438[机械工程—光学工程]