2D MRCP联合静脉注射钆喷酸葡胺的应用价值初探  

A Preliminary Study on the Application Value of 2D MRCP Combined with Intravenous Gadolinium Injectetic Meglumine

作　　者：张炜[1] 肖艳[1] 丁颖[1] 杨琨[1] 陈薇[1] 杨舟 叶天和[1] 杨炼 ZHANG Wei;XIAO Yan;DING Ying(Department of Radiology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei Province 430022,P.R.China)

机构地区：[1]华中科技大学同济医学院附属协和医院放射科,分子影像湖北省重点实验室,武汉430022

出　　处：《临床放射学杂志》2024年第6期1017-1020,共4页Journal of Clinical Radiology

摘　　要：目的 探讨2D磁共振胰胆管成像(MRCP)联合静脉注射钆喷酸葡胺(Gd-DTPA)改善MRCP图像质量的应用价值。方法 搜集2022年10月至2023年4月因胰胆管系统疾病接受MRCP及肝胆增强扫描的患者,经纳入排除标准后最终70例患者纳入研究,患者先行MRI常规平扫,再分别行Gd-DTPA增强前(对照组)及增强后3 min(实验组) 2D MRCP检查。两组图像均传至后处理工作站,由两名高年资医师采用双盲法对MRCP图像进行评分;测量并比较胆总管、胰管中段、背景组织信号强度(SI)及信噪比(SNR),胆总管的对比噪声比(CNR)。结果 实验组评分(4.58±0.41)高于对照组评分(3.78±0.47),差异有统计学意义(P<0.001);对照组胆总管、胰管、背景组织SI分别为131.9±92.6、37.7±23.8、3.5±0.38,实验组胆总管、胰管、背景组织SI分别为146.4±101.0、45.4±29.8、1.8±0.21,注射对比剂3 min后MRCP图像,胆总管及胰管SI均升高,背景组织SI降低,差异有统计学意义(P<0.001);对照组CNR和SNR分别为68.1±48.3和12.9±12.7,实验组CNR和SNR分别为122.8±88.7和38.2±24.8;实验组胆总管及胰管中段CNR、SNR均提高,差异有统计学意义(P<0.001)。结论 静脉注射Gd-DTPA 3 min后MRCP图像背景抑制良好,图像的SNR、CNR显著提高,背景组织SI降低,明显改善MRCP图像质量。Objective To explore the value of 2D MRCP combined with intravenous gadolinium gluumine to improve MRCP image quality.Methods Patients who received MRCP and hepatobiliary enhancement examination in our hospital for pancreaticobiliary disease from October 2022 to April 2023 were selected.70 patients were included in the exclusion criteria for routine MRI scan and 2D MRCP examination before the Gd-DTPA enhancement(control group)and 3 min after the Gd-DTPA enhancement(experimental group).Both groups of images were transmitted to the post-processing workstation,and two senior physicians in our department scored the MRCP images by double-blind method;Measured and compared the signal intensity(SI)and signal noise ratio(SNR)of the common bile duct,middle pancreatic duct,and the contrast noise ratio(CNR)of the common bile duct.Results The score of the experimental group(4.58±0.41)was higher than that of the control group(3.78±0.47),and the difference was statistically significant;in the control group,the common bile duct,pancreatic duct,and background tissue SI were 131.9±92.6,37.7±23.8,and 3.5±0.38,in the experimental groups,the common bile duct,pancreatic duct and background tissue SI were 146.4±101.0,45.4±29.8 and 1.8±0.21,MRCP images after contrast injection3min later,the common bile duct and pancreatic duct SI increased and the background tissue SI decreased,a statistically significant difference(P<0.001);In the control group,the CNR and SNR were 68.1±48.3 and 12.9±12.7,in the experimental group CNR and SNR were 122.8±88.7 and 38.2±24.8,The CNR and SNR of the common bile duct and the middle pancreatic duct in the experimental group were improved,the difference was statistically significant(P<0.001).Conclusion After intravenous injection of Gd-DTPA 3 min,the SNR and CNR were significantly increased,and the background tissue SI decreased,which significantly improved the MRCP image quality.

关 键 词：2D MRCP 钆喷酸葡胺(Gd-DTPA) 静脉注射 图像质量 

分 类 号：R445.2[医药卫生—影像医学与核医学] R575.7[医药卫生—诊断学]