苯磺酸氨氯地平联合厄贝沙坦氢氯噻嗪治疗Ⅱ级以上高血压的效果及评价  

The efficacy and evaluation of amlodipine besylate combined with irbesartan and hydrochlorothia-zide in the treatment of hypertension above grade Ⅱ

作　　者：林培良 Lin Peiliang(Nangiao Hospital,Nan'an City,Fuyjian Promince,362311)

机构地区：[1]福建省南安市南侨医院,福建南安362311

出　　处：《辽宁医学杂志》2024年第3期31-34,共4页Medical Journal of Liaoning

摘　　要：目的评析Ⅱ级以上高血压病人选择“苯磺酸氨氯地平+厄贝沙坦氢氯噻嗪”这两种药物的临床应用价值。方法以80例Ⅱ级以上高血压病人为研究对象,对其科学分成2小组,其分别是:实验组(苯磺酸氨氯地平+厄贝沙坦氢氯噻嗪)与对照组(苯磺酸氨氯地平),统计对比2组的临床疗效、不良反应率、血压及心率等指标变化;另外,还需要统计对比2组的生活质量、肾功能水平等。结果两组患者的疗效、治疗安全性和治疗后的血压水平等指标差异有统计学意义,其中实验组的各项观察指标改善情况均要优于对照组,P<0.05。结论Ⅱ级以上高血压患者联用苯磺酸氨氯地平+厄贝沙坦氢氯噻嗪能够发挥积极的降压作用,同时其临床应用疗效相对安全,有利于提高病患的肾功能,促使其睡眠质量、生活品质等得到显著提高,所以临床一线应用功能突出。Objective To evaluate the clinical application value of amlodipine besylate+irbesartan hydrochlorothiazide in patients with hypertension above grade Ⅱ.Methods 80 patients with hypertension of grade Ⅱ or above were studied and scientifically divided into two groups:the experimental group(amlodipine besylate+irbesartan hydrochlorothiazide)and the control group(amlodipine besylate).The clinical efficacy,adverse reaction rate,blood pressure,heart rate,and other indicators of the two groups were statistically compared;In addition,it is necessary to statistically compare the quality of life,renal function levels,etc.between the two groups.Results There were significant differences in the efficacy,treatment safety,and post treatment blood pressure levels between the two groups of patients,with the experimental group showing better improvement in all observed indicators compared to the control group(P<0.05).Conclusion The combination of amlodipine besylate and irbesartan hydrochlorothiazide can exert a positive antihypertensive effect in patients with hypertension of grade II or above.At the same time,its clinical application efficacy is relatively safe,which is beneficial for improving the renal function of patients,promoting significant improvements in their sleep quality,quality of life,etc.Therefore,its firstline clinical application function is prominent.

关 键 词：苯磺酸氨氯地平 厄贝沙坦氢氯噻嗪 高血压 

分 类 号：R544.1[医药卫生—心血管疾病]